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关键词： Electronics and devices Semiconductors  

摘要： In this paper, it has been shown that employing an underlap channel created by using the dual spacers in dopant-segregated Schottky barrier (DSSB) SOI MOSFET not only reduces the off-state leakage, short-channel effects and the parasitic overlap capacitances but also suppresses the variability induced by process fluctuations in the Schottky barrier height, dopant-segregation length and SOI film thickness of the device. However, the reduced effective gate voltage due to voltage drop across the underlap lengths also reduces the on-state drive current of the device. To alleviate this trade-off, a novel dual-k spacer underlap channel DSSB SOI structure has also been proposed in which the increased fringing electric field effect due to high-k inner spacer layer not only improves the on-state drive current but also reduces the off-state leakage current in both n-channel and p-channel devices. Despite the presence of high-k inner spacer layer increasing the fringing gate capacitance, the scalability in an optimized dual-k spacer underlap structure has improved by similar to 60% and similar to 35%, respectively over the conventional spacer overlap and underlap channel structures. In addition, the variability in an optimized dual-k spacer underlap structure has also been reduced by similar to 50% and similar to 30% respectively over the conventional spacer overlap and underlap channel structures. This clearly indicates that the proposed dual-k spacer underlap structure is a better choice for low-variability nanoscale CMOS logic circuits. The detailed fabrication flow of this novel device has also been proposed which demonstrates the use of conventional CMOS processes.

关键词： Mesenchymal stem cell  

摘要： The use of tendon-derived stem cells (TDSCs) as a cell source for musculoskeletal tissue engineering has not been compared with that of bone marrow stromal cells (BMSC). This study compared the mesenchymal stem cell (MSC) and embryonic stem cells (ESC) markers, clonogenicity, proliferative capacity, and multilineage differentiation potential of rat TDSC and BMSC in vitro. The MSC and ESC marker profiles of paired TDSC and BMSC were compared using flow cytometry and quantitative real-time polymerase chain reaction (qRT-PCR), respectively. Their clonogenicity and proliferative capacity were compared using colony-forming and 5-bromo-2'-deoxyuridine assays, respectively. The expression of tenogenic, osteogenic, and chondrogenic markers at basal state were examined using qRT-PCR. Their osteogenic, chondrogenic, and adipogenic differentiation potentials were compared using standard assays. TDSC and BMSC showed similar expression of CD90 and CD73. TDSC expressed higher levels of Oct4 than BMSC. TDSC exhibited higher clonogenicity, proliferated faster, and expressed higher tenomodulin, scleraxis, collagen 1 proportional to 1 (Col1A1), decorin, alkaline phosphatase, Col2A1, and biglycan messenger RNA levels than BMSC. There was higher calcium nodule formation and osteogenic marker expression in TDSC than BMSC upon osteogenic induction. More chondrocyte-like cells and higher glycosaminoglycan deposition and chondrogenic marker expression were observed in TDSC than BMSC upon chondrogenic induction. There were more oil droplets and expression of an adipogenic marker in TDSC than BMSC upon adipogenic induction. TDSC expressed higher Oct4 levels, which was reported to positively regulate mesendodermal lineage differentiation, showed higher clonogenicity and proliferative capacity, and had greater tenogenic, osteogenic, chondrogenic, and adipogenic markers and differentiation potential than BMSC. TDSC might be a better cell source than BMSC for musculoskeletal tissue regeneration.

关键词： 分离工程   双语教学   教学法  

摘要： 《分离工程》是化学工程专业的主干课程,文章阐述了《分离工程》双语教学的目标及特点,总结了开设分离工程双语教学过程中的一些经验和体会。双语教学在综合学生的英语能力与专业知识的基础上,确定合理的授课模式。通过对教学环节的综合设计,为双语教学这一新颖的教学模式在《分离工程》教学中的实际应用积累了一定经验。

关键词： 膜分离系统   膜过滤   膜分离技术   责任   工程   合肥   纯化   脱盐  

摘要： 世杰是专业致力于膜分离技术研发和膜分离系统制作的高科技股份制公司，是中国膜工业协会理事单位。公司拥有先进的陶瓷微滤、陶瓷超滤、陶瓷复合（特种）、有机超滤、纳滤、反渗透以及工业化膜集成工艺技术，专业为客户提供全方位的膜技术咨询（膜技术服务与支持）、成套膜分离系统设计、制作、安装、调试、维护、操作培训以及膜分离单元的工艺设计、工艺创新、工艺整合等专业服务。

关键词： 膜分离系统   膜过滤   责任   工程   合肥   纯化   脱盐   专家  

摘要： 世杰是专业致力于膜分离技术研发和膜分离系统制作的高科技股份制公司，是中国膜工业协会理事单位。

关键词： 工程建设招投标   审计建议   人员分离   秭归县   行政服务中心   监督管理   工程建设项目   运行机制  

摘要： 秭归县在治理工程建设领域突出问题审计中．根据建设单位项目中存在的规避招投标、违法分包、低价中标、高价结算等问题，向县政府提出工程建设项目在行政服务中心统一招投标．并实行招投标监督管理办公室与招投标中心“管”“办”分离的审计建议．日前县政府采纳这一审计建议。县招投标监督管理局和综合招投标管理办公室在县行政服务中心成立运行．由过去“分散”在各个部门的建设项目招投标．集中在县行政服务中心综合招标投标，实行“五统一”招投标监管模式全覆盖．卖现招投标监督管理局与综合招投标中心机构分设、人员分离、财务分账、职能分离的“管”、“办”运行机制。

摘要： Background Patients with chronic kidney disease (CKD) experience poor outcomes after acute myocardial infarction (AMI). We sought to compare clinical characteristics of advanced CKD, dialysis, and non-CKD patients hospitalized with AMI. Methods This observational study used record-linked data from the US Renal Data System and Third National Registry of Myocardial Infarction to identify 2,390 dialysis patients with AMI hospitalizations between April 1998 and June 2000. Advanced CKD patients (n = 29,319) were identified by baseline creatinine level >= 2.5 mg/dL. Clinical characteristics of CKD, dialysis, and non-CKD patients (n = 274,777) were compared using the chi(2) test. Results Clinically significant differences among patients with advanced CKD (dialysis and non-CKD, respectively) on admission were chest pain, 40.4% (41.1% and 61.6%);diagnosis other than acute coronary syndrome, 44% (47.7% and 25.8%);and ST elevation, 15.9% (17.6% and 32.5%). In-hospital adverse outcomes were mortality, 23% (21.7% and 12.6%);unexpected cardiac arrest, 8.9% (12.3% and 6%);congestive heart failure, 41% (25.8% and 21.1%);and major bleeding, 4.9% (4.4% and 3%);P < .001 for all comparisons. In a logistic regression model, the adjusted odds ratio for in-hospital mortality for CKD (vs non-CKD) patients was 1.44 (95% CI 1.39-1.49). Conclusions The clinical characteristics of non-dialysis-dependent, advanced CKD patients with AMI are similar to characteristics of dialysis patients and likely contribute to poor outcomes. Intensive efforts for timely, accurate recognition of AMI in advanced CKD patients are warranted. (Am Heart J 2012;163:399-406.)

关键词： 药物分离工程   CDIO   教学模式   课程建设  

摘要： 文章介绍了通过融合国际工程教育中先进的CDIO工程理念,在《药物分离工程》课程教学改革方面所做的一些尝试与收获。通过确立新的教学目标和教学大纲,借助团队协作项目设计的目标任务形式,结合过程监控与课程考核方式的调整,构建起基于"能力-素质-知识"架构的课程教学与学生综合工程能力培养的新模式。

关键词： 北京科技大学   气体分离   化工产品   空气   技术   开发   分离工程   能源利用  

摘要： 空气化工产品公司（Air Products，简称空气产品公司），最近宣布与北京科技大学签署一项联合研发协议。协议称将和北京科技大学气体分离工程研究所合作，共同开发先进技术模型，提高气体分离过程中的能源利用和资本效率。

关键词： 分离式   闸室   结构   设计  

摘要： 对镇江市引航道水利枢纽工程闸室结构型式进行了分析比较,并对分离式闸室结构的闸墩与底板的连接型式进行了优化设计,使得工程施工更加方便,而且改善了底板和闸墩的应力条件,并节省了工程投资。实施后工程运行情况良好。