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关键词： Upper-Division Undergraduate   Biochemistry   Curriculum   Interdisciplinary/Multidisciplinary   Public Understanding/Outreach   Communication/Writing   Problem Solving/Decision Making   Applications of Chemistry  

摘要： A recent push toward addressing antiracism in science reveals a need to integrate discussions of racism, social justice, and equity into undergraduate STEM classes. Toward this end, in Fall 2020, a theme of "Racism is a Public Health Emergency" was incorporated as an overlay for an existing undergraduate biochemistry curriculum. This theme was used throughout the entire semester and involved discussions of racism, social justice, and equity that were directly integrated with the science content of the course. Students enrolled in the class were surveyed at the end of the semester regarding their perceptions of integrating discussions of racism, social justice, and/or equity into chemistry courses. Students indicated that the inclusion of the overlay increased the relevance of the course material, indicated a high level of understanding of the impact of bias and race on the field of biochemistry, and expressed overwhelmingly positive views regarding future inclusion of similar themes of equity and antiracism in chemistry courses. Additionally, student scores and answers on common final exam questions were compared to previous semesters, revealing that the inclusion of this overlay did not negatively impact coverage of biochemistry content.

关键词： 希沃白板5   生物化学   教育教学  

摘要： 希沃白板5作为一种新兴的电子教学工具,是传统黑板与多媒体课件的结合,目前大部分高职院校已经普及希沃白板5,但是其真正的有效使用尚待提高.文章指出了高职院校生物化学的教学现状以及希沃白板5在高职院校生物化学教学中的优势,分析了希沃白板5一些功能在高职院校生物化学教学中的应用,并指出了希沃白板5在教学使用中存在的一些问题,旨在倡导更多高职院校教师使用希沃白板5进行教学,提升生物化学教学质量,培养具有发散思维和创新能力的新时代人才.

关键词： Cremastra appendiculata   Coprinellus disseminatus   Lignin degradation   Transcriptome analysis   Seed germination  

摘要： Background Cremastra appendiculata is a rare terrestrial orchid with a high market value as an ornamental and medicinal plant. However, the species depends entirely on fungi for seed germination under natural conditions. In a previous study, we have successfully isolated and identified the mycorrhizal fungus Coprinellus disseminatus which was able to induce the germination of C. appendiculata seeds. We then speculated that C. disseminatus may do so by breaking the testa imposed dormancy of the seeds. In this study, biochemical and transcriptomic analyses were used to characterize the germination of C. appendiculata seeds, collected at different stages of germination, as affected by C. disseminatus. Results The lignocellulose in the seeds coat of C. appendiculata was degraded by the mycorrhizal fungus resulting in facilitated absorption of water. The rate of decline in lignin content was 67 and 73% at 6 and 12 days after sowing, respectively. The water content increased from 13 to 90% during symbiosis. A total of 15,382 genes showing significantly different levels of expression (log(2) FPKM >= 2.0, Qvalue <= 0.05) were successfully identified among all libraries, where the highest number of DEGs was shared between 6 days versus 0 day after symbiotic germination. Gene annotation results suggested that 15 key genes related water-status, such as DHN gene family and Xero 1 were down-regulated. The genes zeaxanthin epoxidase ZEP, 9-cis-epoxycarotenoid dioxygenase NCED3 and beta-carotene hydroxylase involved in the biosynthesis of abscisic acid (ABA) were significantly down-regulated in 6 days as compared to 0 day after symbiotic germination. Conclusions This work demonstrates that mycorrhizal fungus C. disseminatus can stimulate C. appendiculata seeds germination through a mechanism of breaking the testa imposed dormancy and inducing water absorption of the embryo.

关键词： 医学生物化学教学   学习成绩   综合能力   临床案例教学法  

摘要： 比较临床案例教学法在医学生物化学教学中的应用效果,为临床实践提供理论依据。方法以140例医学生物化学教学学生为对象,分为参照组70例(常规教学)与研究组70例(临床案例教学法),对比两种教学方式的应用效果。结果 两组理论成绩、实践成绩、综合能力评分,研究组与参照组更高,P<0.05。对于参与积极性,研究组是100%,参照组是85.71%;对于临床技能掌握情况,研究组是97.14%,参照组是71.43%,差异P<0.05。对于满意度,研究组是100%,参照组85.71%,差异P<0.05。结论 医学生物化学教学中采用临床案例教学法,可有效提高学生的学习成绩,同时还可培养其综合能力,得到学生的满意评价,其应用效果显著,可广泛应用于临床。

关键词： 融合教学模式   慕课   生物化学   设计与实践  

摘要： 目的探讨基于慕课的融合式教学模式在生物化学课程教学实践中的效果。方法选择中医临床医学班作为实验对象,随机选择实验班和对照班,以生物化学课程作为教学基本内容,实验班采用基于慕课的融合式教学模式,对照组采用一般混合式教学模式。通过课程测验和问卷调查对教学效果进行评价。结果基于慕课的融合式教学模式提高了学生对生物化学课程学习的自主性和能动性,促进了师生交流和生生交流的频率,提高了学生的学习成绩。结论基于慕课的融合式教学模式能提高生物化学的教学效果,应加强推广应用。

关键词： 微教学   生物化学   微课堂  

摘要： 随着微教学时代的到来,高校教师不能再沿袭以往的传统教学授课模式,传统教学模式必须进行相应的改革。开展微课教学,不仅能加强师生之间的互动与交流,还能激发学生学习的主动性,提高教学质量。“生物化学”是生物学专业的一门基础性课程,不仅课程内容多、知识点零散,而且在教学过程中容易形成学生被动学习的局面。所以,更新教学理念,改变教学手段,最终达到以符合时代发展的便捷教学方法为学生传道解惑的目的非常重要。以“生物化学”核心课程为例,探讨微教学的发展背景、特点、优势,以及在“生物化学”课程中的具体应用,为其他课程开展微课堂建设提供有效参考。

关键词： 医学生物化学   实验教学   混合式教学  

摘要： 医学生物化学是医学专业的核心课程之一,实验教学是重要组成部分。本文对医学生物化学实验教学内容和教学方式进行改革,以提升教学质量,充分发挥课程的育人作用,同时激发学生的积极性,提高创新能力和综合素质。

关键词： 互联网+   生物   教学   实验   化学   教育  

摘要： “互联网+教育”时代的到来使得各类现代化的信息技术与教育教学实现了更深层次的融合,在为教学提供便利条件的同时,也对传统教学模式带来了巨大挑战。基于此,通过开展生物化学实验教学模式的相关研究,在明确该课程实验教学改革驱动因素的基础上,针对缺失线上教育渠道、师生课下交互性不强、教学考核指标单一等现有教学模式存在问题,提出建立线上虚拟实验室与手机端平台、创新“课程 课下”协同反馈机制、构建生物化学实验立体化考核体系等创新策略,以期为促进生物化学实验教改的可持续发展提供创新思路。

关键词： 混合教学   微课资源   医学生物化学  

摘要： 随着科学技术不断发展,出现了很多新型教育模式,目前部分高校已经开始使用线上线下混合教学模式,微课资源也应运而生,成为高等教育未来的发展方向。在线上线下混合教学模式的基础上,将微课资源融入到医学生物化学教学过程中,可以对教学内容进行拓展,教师能够实现课堂教学与个性化教学兼顾,能够及时解决学生在学习过程中遇到的问题,提升教学效果和教学效率。本文对微课的概念以及在我国的发展现状进行阐述,指出了医学生物化学混合式教学的设计原则,并对医学生物化学的微课资源开发与应用分别进行了探讨,希望为相关研究提供借鉴和参考。