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关键词： 网络教学   医学生理学教学   研究性学习  

摘要： 结合生理学教学改革,从网络课程内容和网络环境下生理学研究性学习模式方面介绍了网络教学的开展和应用,指出网络教学在医学生理学教学中的应用可提高医学生独立获取知识、信息综合分析及创新能力。

关键词： 病理生理学   实验教学   教学质量  

摘要： 病理生理学是基础医学教育的一门主干课程，是联系基础与临床的桥梁，实践性很强。实验研究是病理生理学研究和发展的主要手段和动力。在病理生理学教学中，实验课占有重要地位，是提高病理生理学教学质量不容忽视的一部分。因此，优化病理生理学实验课教学方法，提高学生的积极性、主动性，增强实验课教学效果，加强学生能力培养，对提高病理生理学教学质量具有至关重要的作用。

关键词： 启发式教学方法   医学生素质   生理学教学   教学过程   教学方式   生理教学  

摘要： 启发式教学是指教师在教学过程中,把讲解与学生思考有机地结合起来,充分调动学生的主动性和积极性,引导学生积极思维,从中发现问题、分析问题和解决问题,融会贯通地掌握知识和技能的一种教学方式。下面浅谈几种启发式教学方法在生理教学中的运用。

关键词： 中国生理学会   创新型人才   实验教学   实验技术   讲习班   培养   研究型实验   实验中心  

摘要： 我们于2007年7月16日-22日参加了由中国生理学会主办，浙江大学医学院基础医学实验中心生理学与药理学实验室共同承办的“2007年全国现代生理学实验技术和研究创新型实验教学讲习班”，在学习班上夏强教授首先进行了“研究型实验教学理论与实践”的演讲，随后陆源老师采用先进的实验方法、

关键词： Animals   Biocompatible Materials   Cell Physiology   Humans   Nanostructures   动物   生物相容性材料   细胞生理学   表面特性   Nanostructure   Biocompatible Materials   Cell Physiological Phenomena   cytology   physiographic features  

摘要： Chemical and topographic substrate surface patterning is recognized as a powerful tool for regulating cell functions. We discuss the relative role of scale and pattern of chemically and topographically patterned surfaces in regulating cell behavior. Chemical patterning achieved using spatial cell-adhesive molecular organization regulates different cell functions depending on its scale (micropattern for cell patterning and derived cell functions, nanopattern for collective cell functions such as adhesion, proliferation, and differentiation). In chemical patterning, a direct and specific cell-sensing mechanism such as integrin-ligand binding governs. Alternatively, topographic modification affects different cell functions depending on its pattern (anisotropic ridges and grooves for contact-guided cell alignment, isotropic textures having randomly or evenly distributed topographic features for collective functions). For all topographic patterns, micro- or nanotopographic scale determines whether specific cell reactions occur. If the topography effect were assessed under the same surface chemistry, cell adaptation processes would play a major role in cell sensing and response to topography, largely independent of mediation via differences in adsorbed proteins. Controlling scale and pattern in chemical and topographic substrate patterning would help significantly to develop purpose-specific cell-regulating cues in various biomedical applications, including tissue engineering, implants, cell-based biosensors, microarrays, and basic cell biology.

关键词： .intracrine   Intracellular renin-angiotensin  

摘要： The article discusses a research by V.P. Singh and colleagues published in an issue of the "American Journal of Physiology-Heart and Circulatory Physiology," which presents data indicating the intracellular synthesis and nuclear trafficking of angiotensin II in neonatal cardiac myocytes stimulated by high glucose or isoproterenol. The authors raised issues regarding the site of synthesis of any angiotensin II that might be active in the intracellular space.

关键词： 课程建设   整体效益   师范教育   培养目标   素质结构  

摘要： 高等师范教育的课程建设既要反映和体现现代科学文化的先进水平和科学发展特点,又必须主动适应我国新一轮的基础教育改革与新课程标准实施的需要。运动生理学是体育院校各专业的主干课程,在人才培养中起到承前启后的重要作用。总结整理近年来运动生理学课程建设工作的尝试性改革和体会,以求进一步深化和完善高师体育教育专业的整体效益和水平的不断提高。

关键词： 运动生理学   还原论   进化论   相关因果论  

摘要： 从百余年运动生理学的研究理念和方法来看,存在还原论、进化论和相关因果论对运动生理现象的合理化解释,这三种科学范式对于生命现象的解释有助于人们理解运动生理学的内在规律,但存在一定误导性。运动生理学研究中对生命现象的解释应保持慎重。

关键词： 实验教学   生理学   改革  

摘要： 针对我院实际情况,进行生理学实验教学改革探索。通过精编实验指导,设定常规和备选实验内容、项目,增开学生设计性实验等,优化实验教学流程,以加强学生技能训练,促进学生应用能力与创新意识的培养为目的,实现了生理学实验课高效和低耗性,提高了实验课教学质量。

关键词： EVOLUTION (Biology)   JERUSALEM crickets   GENETIC polymorphisms   QUANTITATIVE genetics   INSECTS -- Physiology  

摘要： Predicting evolutionary change is the central goal of evolutionary biology because it is the primary means by which we can test evolutionary hypotheses. In this article, we analyze the pattern of evolutionary change in a laboratory population of the wing-dimorphic sand cricket Gryllus firmus resulting from relaxation of selection favoring the migratory (long-winged) morph. Based on a well-characterized trade-off between fecundity and flight capability, we predict that evolution in the laboratory environment should result in a reduction in the proportion of long-winged morphs. We also predict increased fecundity and reduced functionality and weight of the major flight muscles in long-winged females but little change in short-winged (flightless) females. Based on quantitative genetic theory, we predict that the regression equation describing the trade-off between ovary weight and weight of the major flight muscles will show a change in its intercept but not in its slope. Comparisons across generations verify all of these predictions. Further, using values of genetic parameters estimated from previous studies, we show that a quantitative genetic simulation model can account for not only the qualitative changes but also the evolutionary trajectory. These results demonstrate the power of combining quantitative genetic and physiological approaches for understanding the evolution of complex traits.