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关键词： 高等医学教育   病理生理学   实验教学   课程改革  

摘要： 为培养21世纪需要的基础知识扎实,具有创新能力的高素质人才,要求高等医学教育在进行教学内容和课程体系改革的同时,还要探讨一套有效的教学方法和手段。作者在病理生理学(以下简称病生)实验教学中进行了改革,开设了设计性实验课程,旨在启发学生的科学思维和创新精神,培养他们独立分析问题、解决问题的能力。[第一段]

关键词： 解剖生理学实验教学   学生   创新能力  

摘要： 以现代教育理论为指导,从试验教学过程的构建、实验教学模式的改革、试验教学大纲及成绩评价体系的完善等方面探讨解剖生理学实验教学中提高学生创新能力的方法及措施。

摘要： 为推动全国临床肌电图与电生理研究学术进展,加强学术交流,中华医学会神经病学分会肌电图与临床神经电生理学组和中华神经科杂志编辑委员会拟定于2008年7月3—7日在宁夏回族自治区银川市举行第十届全国肌电图与临床神经电生理学术会议暨规范化研讨会。会上将邀请汤晓芙、康德碹、沈定国、崔丽英、樊东升、王玉平、张通等肌电图和临

关键词： 科学实验   运动训练   教学质量   运动生理学   运动生物力学   运动生物化学   动手能力   运动解剖学  

摘要： 运动人体科学实验是运动训练专业开设的实验课程,它包括运动解剖学、运动生理学、运动生物力学、运动生物化学和体育保健学等多学科实验内容,是体育院校中诸多专业都要涉及的重要的专业基础教学内容,是运动训练专业教学体系的重要组成部分。通过实验教学可帮助学生理解、掌握和运用理论知识,使学生掌握科学的思维方法,形成科学严谨的精神和团结协作的作风;培养和提高学生的动手能力,培养和提高学生思考问题、发现问题、分析问题和解决问题的能力;能更好地体现学生的“主体”地位,培养学生创新意识和能力。[第一段]

关键词： poly(vinylidene diflouride)   wistar mice   strength sensor   gait analysis  

摘要： A group of force sensors was designed and manufactured. These are based on piezoelectric poly(vinylidene diflouride) (PVDF) films. These sensors will help evaluate the revascularization process in Wistar mouse legs. The sensors were calibrated from 0.0 to 14.4 g and had an uncertainty of +/- 7.5 mN.

关键词： laboratory rats   sleep   welfare   husbandry procedures  

摘要： Research has indicated that chronic stress can reduce sleep quality and quantity. Yet there has been little investigation into whether husbandry procedures carried out during an animal's normal sleeping period affect subsequent sleep behaviour and welfare. We housed 48 rats in enriched cages containing four rats, in either a light phase treatment (LPT) (n = 6 cages) or a dark phase treatment (DPT) (n = 6 cages). Rats in the LPT were exposed to husbandry procedures (e.g. weighing, cleaning) during the light phase when we would expect them to be inactive/sleeping, three times every week. DPT rats experienced the same procedures, but during the dark phase when we would expect them to be active/awake. After five weeks, behaviour for all cages was sampled over 12 It of both the light and dark phase. General health measures (e.g. body weight) were collected over the five weeks housing period, and organ weights (e.g. thymus) were recorded post-mortem. Principal component analyses yielded four factors, two of which revealed treatment differences. For one, loading positively on chromodacryorrhoea score and negatively on sleep, self-grooming and enrichment directed behaviour, LPT rats scored higher than DPT rats. The other loaded positively for relative thymus weight and activity and negatively for aggression and social interaction. DPT rats scored higher on this than LPT rats. LPT rats thus displayed indicators of reduced welfare (e.g. less sleep, elevated chromodacryorrhoea, lighter thymus glands, higher aggression) relative to DPT rats. Therefore, husbandry procedures applied in the dark rather than the light phase might improve the welfare of laboratory rats. (C) 2007 Elsevier B.V. All rights reserved.

关键词： 生理学   实验   高等学校：技术学校   教材  

ISBN: (纸本)7506738988

摘要： 本书是全国医药职业教育药学类规划教材之一，依照教育部（2006）16号文件要求，结合我国高职教育的发展特点，根据《生理学实验》教学大纲的基本要求和课程特点编写而成。全书共分为9章28个实验，第一章总论介绍生理学实验基础知识，其他各章介绍了各系统的主要生理功能特点实验以及基本组织的观察，每个实验包括实验目的、实验原理、实验材料与器械、实验方法和步骤、思考题等。本教材由易到难，图文并茂，具有较强的实用性，还能够开发学生的创新设计实验能力。本书适合医药高职教育及专科、函授和自学考试等相同层次不同办学形式教学使用，也可作为医药行业培训和自学用书。

关键词： endogenous morphine   mu(3) opiate receptor   nitric oxide   stem cell   cancer  

摘要： Cancer is a simplistic, yet complicated, process that promotes uncontrolled growth. In this regard, this unconstrained proliferation may represent primitive phenomena whereby cellular regulation is suspended or compromised. Given the new empirical evidence for a morphinergic presence and its profound modulatory actions on several cellular processes it is not an overstatement to hypothesize that morphine may represent a key chemical messenger in the process of modulating proliferation of diverse cells. This has been recently demonstrated by the finding of a novel opiate-alkaloid selective receptor subtype in human multilineage progenitor cells (MLPC). Adding to the significance of morphinergic signaling are the findings of its presence in plant, invertebrate and vertebrate cells, which also have been shown to synthesize this messenger as well. Interestingly, we and others have shown that some cancerous tissues contain morphine. Furthermore, in medullary histolytic reticulosis, which is exemplified by cells having hyperactivity, the mu3 (mu(3)) opiate select receptor was not present. Thus, it would appear that morphinergic signaling has inserted itself in many processes taking a long time to evolve, including those regulating the proliferation of cells across diverse phyla. (C) 2007 Elsevier Ltd. All rights reserved.

关键词： Genes   Control loops   Molecules   Circadian rhythm   Negative feedback   Clocks   Gene expression   Neurons   Physiology  

摘要： Models of circadian timekeeping mechanisms in plants, flies, and mammals are expanding to include intracellular small-molecule signals.

关键词： 教学资源库   教学方法   生理学   教育信息化  

摘要： 医学生理学的教学过程中,教学资源的建设和共享是顺利开展教学工作,保证和提高教学质量,有效地利用教学的时间和空间,提高教学效率的重要环节。在分析医学生理学教学资源建设及应用的基础上,提出了以网络资源与课程整合的病案教学资源建设,教学内容的引导性和重点化网上资源建设,医学生理学试题库教学资源建设等为基础,探索推进医学生理学教学资源建设与应用的有效途径。