教学课程资源库 更多>>

关键词： 医学生理学   外国教材   评估体系   评估指标  

摘要： 外国医学生理学的课程设置和教材编写与国内存在较大差异。图书馆可以选取作者知名度、出版情况、馆藏情况、大学利用情况、图书被引用情况、业内评价情况和销售情况等作为外国医学生理学教材的评估指标,依据不同指标的重要程度赋予相应的分值,最终建立易于使用的外国医学生理学教材复选评估体系。

关键词： 自主性综合实验   创新能力培养   植物生理  

摘要： 当前的大学生由于长时间的应试教育,普遍存在追求标准答案,学习被动,没有创新意识,团队意识薄弱等特点,华东师范大学植物生理学实验课通过设置半自主的综合实验尝试解决这一问题。该实验由教师指定科学问题和实验材料,学生自己决定并完成研究方案、研究进程和研究结果分析。教师的指导强调建议和启发,成绩评价侧重态度和过程,鼓励创造性地完成实验。通过该实验的学习,学生们普遍反映真正体会到了什么是创新和学以致用,对科研的兴趣和自信明显提高。

关键词： 心理学专业   人体解剖生理学   教学质量  

摘要： 人体解剖生理学是心理学专业的基础理论课程,作者在教学过程中通过创建趣味课堂、调整教学重点、充分与学生互动和注重归纳总结等方面探讨人体解剖生理学教学方法,取得了良好的教学效果。

关键词： 肌萎缩侧索硬化症(ALS)   神经电生理学  

摘要： 目的:观察神经电生理检查在肌萎缩侧索硬化症(amyotrophic lateral sclerosis,ALS)中的应用价值。方法:分别对28例临床确诊ALS、6例临床拟诊ALS、4例临床可能ALS患者进行4个区域的共8块肌肉肌电图(EMG)分析,四肢的磁运动诱发电位(MEP),上肢正中神经、尺神经、下肢胫神经F波检查,在双侧腓肠肌记录H波,四肢远端神经传导测定,包括运动传导速度(MCV)、感觉传导速度(SCV)、复合运动神经动作电位(CMAP)、感觉神经动作电位(SNAP)以及运动末梢潜伏期(DML)进行测定并分析,并与健康对照组30例进行比较。结果:临床确诊ALS的神经电生理测定各值异常均高于拟诊ALS和可能ALS(P<0.05),拟诊ALS和可能ALS组比较没有明显统计学差异。ALS组EMG异常率85%,MEP异常率72.4%,神经传导异常主要表现为CMAP降低36.2%,SCV基本正常,F波出波率下降33.3%,F波振幅增高26.3%,H波振幅增高26.3%。结论:EMG对ALS患者下运动神经元损害有定位诊断价值,EMG是ALS诊断的重要依据;MEP对ALS患者上运动神经元损害有诊断价值,但特异性不高;F波、H波对ALS患者上下神经元神经损害定位有补充诊断价值,神经传导测定用于ALS的鉴别诊断。

关键词： 教学方法   动物生理学实验   探讨分析  

摘要： 该文针对动物生理学实验在动物生理学教学中的重要作用，从生物机能实验系统的应用、合理调整和科学安排实验内容、开设设计性实验和适当穿插示范、加强操作规范化训练等几方面．阐述了动物生理学实验课教学法的改革与实践。

关键词： Integrated cell-based biosensor   Light-addressable potentiometric sensor (LAPS)   Electrical cell-substrate impedance sensor (ECIS)   Cellular growth and metabolism   In vitro drug analysis  

摘要： The study presented a novel integrated cell-based biosensor with light-addressable potentiometric sensor (LAPS) and electrical cell-substrate impedance sensor (ECIS). The integrated cell-based biosensor was fabricated in order to monitor the cellular metabolism and growth status by LAPS and ECIS. Moreover, the specific instrument was established for controlling the detection processes. Sensor test and cell experiments were carried out to determine the performance of integrated sensor. The result showed that integrated biosensor can monitor the change of cell electrical impedance and extracellular acidification simultaneously which can be used for drug evaluation by monitoring cell growth status (e.g. cell number, adhesion, and morphology) and cell energy metabolism status (e.g. extracellular acidification) in real time. With the development of sensor technology, the integrated cell-based biosensor will be a utility platform to study the mechanism of cellular metabolism and in vitro drug analysis.

关键词： 人体解剖学   人体生理学   高等职业教育   教材  

ISBN: (纸本)9787564142902

摘要： 本书是高职、高专药学专业《人体解剖生理学实训》教材。

关键词： amyloidogenesis   apoptosis   cytotoxic peptides   flip-flop   hydrophobic mismatch   lipid asymmetry   liquid-ordered phase   oxidative stress   oxidized phospholipids   phase segregation  

摘要： The oxidation of lipids has been shown to impact virtually all cellular processes. The paradigm has been that this involvement is due to interference with the functions of membrane-associated proteins. It is only recently that methodological advances in molecular-level detection and identification have begun to provide insights into oxidative lipid modification and its involvement in cell signaling as well as in major diseases and inflammation. Extensive evidence suggests a correlation between lipid peroxidation and degenerative neurological diseases such as Parkinson's and Alzheimer's, as well as type2 diabetes and cancer. Despite the obvious relevance of understanding the molecular basis of the above ailments, the exact modes of action of oxidized lipids have remained elusive. In this minireview, we summarize recent findings on the biophysical characteristics of biomembranes following oxidative derivatization of their lipids, and how these altered properties are involved in both physiological processes and major pathological conditions. Lipid-bearing, oxidatively truncated and functionalized acyl chains are known to modify membrane bulk physical properties, such as thermal phase behavior, bilayer thickness, hydration and polarity profiles, as manifest in the altered structural dynamics of lipid bilayers, leading to augmented membrane permeability, fast lipid transbilayer diffusion (flip-flop), loss of lipid asymmetry (scrambling) and phase segregation (the formation of rafts'). These changes, together with the generated reactive lipid derivatives, can be further expected to interfere with lipid-protein interactions, influencing metabolic pathways, causing inflammation, the execution phase in apoptosis and initiating pathological processes.

关键词： 能量   健康   运动生理学   业余爱好   心理治疗   内在情感   挖掘潜力   身体素质  

摘要： 你可以把敲鼓作为一种业余爱好。心理治疗师认为，敲鼓能够很好地缓解压力，而且趣味性十足，它能把人们的内在情感畅快地表达出来。美国德州农工大学蒂奠西.莱特福特博士通过观察发现，采用敲鼓的方式进行健身颇有挖掘潜力，锻炼者的身体素质得到了明显提高。从运动生理学的角度来看，它是一种非常有效的健身训练方法，锻炼者的全身肌肉群都被调动起来了。

关键词： 岗位胜任力   生理学   实验  

摘要： 岗位胜任力培养是《新世纪医学卫生人才培养》报告提出的第三次医学教育改革的目标。在此目标指引下,通过生理学实验课培养团队合作理念、能力以及动态、整体的认识观念、强化基本功,于岗位胜任力培养的启蒙教育阶段发挥职业入门引导作用。