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关键词： 灰渣混凝土空心隔墙板   相对质量   相对动弹性模量   拟合函数  

摘要： 文章对灰渣混凝土空心隔墙板进行了干湿循环试验,通过电子天平和超声波无损检测技术测量研究对象的相对质量和相对动弹性模量参数,并对其进行曲线拟合得到了最佳拟合函数,最后综合分析了其性能退化规律,以推动其在我国西部地区的发展及应用。

关键词： 屋顶绿化   屋顶花园   植物配置   植物养护  

摘要： 随着城市化的发展,建筑用地面积逐渐扩大,导致绿化用地面积越来越少,两者之间出现难以调和的矛盾,影响城市的可持续发展。屋顶绿化不仅不会额外占用城市土地,还能扩大城市绿化范围,促进改善城市生态环境质量。以屋顶绿化为切入点,在明确屋顶植物配置原则的基础上提出专业可行的配置建议及养护方法,促进屋顶绿化植物健康茁壮生长,扩大城市绿化面积。

关键词： 日照时数   光饱和点   高温胁迫   温度   照度  

摘要： 夏季重庆城区受室外综合温度影响,住宅南向阳台温度高于同一时刻建筑周边绿地地表温度,且阳台植物盆土较浅,在阳光直射条件下植物枝叶及根际易受室外高温的影响,使植物产生温度胁迫作用。在观测时段内对19种阳台植物进行观测,夏至前气温相对较低,极端温度和直射强光积累较少,植物生长环境较佳,夏至之后,受极端温度和直射强光复合作用影响,植物的生长状况变差,甚至部分植物无法生存,但也有一部分阳性且耐热植物仍能保持良好的生长状态,南向阳台植物的选择应关注这类植物。

关键词： Functionally graded carbon nanotube-reinforced composite   Regular polygon built-up structure   Vibration   Flutter   Supersonic airflow  

摘要： The paper is dedicated to the vibration and flutter analysis of functionally graded carbon nanotube-reinforced composite (FG-CNTRC) regular polygon built-up (RPB) structures with general boundary conditions. By employing the first-order shear deformation theory (FSDT) and quasi-steady supersonic piston theory, the energy functional expressions of the system are formulated. The governing equations of the system are derived based on the Hamilton's principle and the solutions for the dynamic problems of the system are obtained by using the modified Ritz method. The accuracy and efficiency of the proposed model are validated by comparing the obtained solutions with those from the FEM and literature. Finally, the effects of the boundary condition, volume fraction of carbon nanotubes (CNT) and CNT distribution on the vibration and flutter characteristics of the CNTRC RPB structures are discussed by carrying out the parametric studies.

关键词： Primary mediastinal B cell lymphoma   MACOP-B   Rituximab   Radiotherapy   Checkpoint inhibitor  

摘要： Primary mediastinal B cell lymphoma is a rare entity and often should be promptly treated as a hematological emergency: The initial treatment decision is crucial for the management of this disease. An observational retrospective study was conducted with the aim to improve information on treatment and outcomes of primary mediastinal B cell lymphoma in real practice. After 12 cycles of MACOP-B regimen (methotrexate, doxorubicin, cyclophosphamide, vincristine, , and prednisone) with or without rituximab, 120 patients out of 151 (79.5%) achieved a complete response and 12 (7.9%) a partial response leading to a global response of 87.4%. The 21-year overall survival is 82.6%;progression-free and disease-free survivals are 69.3% and 86.4%, respectively. Regarding the role of radiotherapy (RT), patients with a negative PET scan after MACOP-B did not undergo RT: One out of these 48 (2.1%) showed a relapse at 11 months. All relapsed/refractory patients who achieved a response with checkpoint inhibitors are still in continuous complete response with a median follow-up of 14 months. Data that we have gathered over a 30-year experience in the treatment of primary mediastinal B cell lymphoma patients clearly indicate that a third-generation chemotherapy regimen such as MACOP-B is feasible and easily deliverable on an outpatient basis. Regarding the unmet medical need of relapsed/refractory patients, new encouraging results occurred with the advent of the checkpoint inhibitors.

摘要： Cell-free fetal DNA analysis has an established role in prenatal assessments. It serves as a source of fetal genetic material that is accessible non-invasively from maternal blood. Through the years, evidence has accumulated to show that cell-free fetal DNA molecules are derived from placental tissues, are mainly of short DNA fragments and have rapid post-delivery clearance profiles. But questions regarding how they come to being short molecules from placental cells and in which physical forms do they exist remained largely unanswered until recently. We now know that the distributions of ending sites of cell-free DNA molecules are non-random across the genome and bear correlations with the chromatin structures of cells from which they have originated. Such an insight offers ways to deduce the tissue-of-origin of these molecules. Besides, the physical nature and sequence characteristics of the ends of each cell-free DNA molecule provide tell-tale signs of how the DNA fragmentation processes are orchestrated by nuclease enzymes. These realizations offered opportunities to develop methods for enriching cell-free fetal DNA to facilitate non-invasive prenatal diagnostics. Here we aimed to collate what is known about the biological and physical characteristics of cell-free fetal DNA into one article and explain the implications of these observations.

关键词： canine   cell culture   corneal endothelial cell   primary cell  

摘要： Objective To establish a primary cell culture and clarify the characteristics of canine corneal endothelial cells in vitro. Procedures The eyes were enucleated from dogs that were euthanized for reasons unrelated to this study. Enucleated canine eyes were dissected, and the intact corneas were isolated from the globes. Using enzymes, the corneal endothelial cells were dispersed from the cornea. The obtained canine corneal endothelial cells were cultured in a cell culture dish. Cultured corneal endothelial cells were morphologically evaluated using phase-contrast microscopy. Immunohistochemical analysis of the cultured cells, particularly of the corneal endothelial cell marker, zonula occludens-1 (ZO-1), Na+/K+-ATPase, and vimentin, was performed to clarify whether the cultured cells were actually corneal endothelial cells. Furthermore, the post-passage morphology of cultured cells was evaluated. Results Canine primary cultured corneal endothelial cells showed morphologically small, cobblestone-like structures. The isolated cells had proliferative ability in vitro and demonstrated positive expression of the corneal endothelial cell markers, ZO-1, Na+/K+-ATPase, and vimentin. However, repeated passages resulted in larger cell sizes as assessed by phase-contrast microscopy. Repeated passages also resulted in lower cell density. Conclusions This study demonstrated the successful culture of canine corneal endothelial cells. This might enhance the understanding of corneal endothelial cell characteristics in dogs.

关键词： Cryptic species   morphology   Phlebotominae   taxonomic problem   vector-borne disease   vector competence   vectors  

摘要： A species complex (= species group, species series) is an assemblage of species, which are related morphologically and phylogenetically. Recent research has revealed several arthropod vector species that were believed to be a single nominal species actually representing a group of closely related species, which are sometimes morphologically indistinguishable at one or more developmental stages. In some instances, differences in terms of vector competence, capacity, or both have been recorded. It highlights the importance of detecting and studying species complexes to improve our understanding of pathogen transmission patterns, which may be vectored more or less efficiently by different species within the complex. Considering more than 540 species, about one-third of the phlebotomine sand flies in the New World present males and/or females morphologically indistinguishable to one or more species. Remarkably, several of these species may act in transmission of pathogenic agents. In this article, we review recent research on species complexes in phlebotomine sand flies from the Americas. Possible practical implications of recently acquired knowledge and future research needs are also discussed.

关键词： 庭院-绿化-景观设计-阳台-绿化-景观设计  

ISBN: (纸本)9787111688631

摘要： 本书通过图文解说的形式，对阳台、露台、小庭院设计中的重要知识点进行深入解析，观点表达具体，文字通俗易懂。以图文结合的编写形式，能够在较大程度上让读者理解要点。书中配有大量精美的案例图片，十分具有代表性，细致到地面材质、绿植种类等。从阳台到露台，再到庭院，手把手教读者打造梦想中的都市花园，满足人们对生活环境的绿化需求。本书使用范围广泛，不仅可以作为普通业主的装修参考书，以及施工管理人员的学习用书，还可以作为庭院设计、景观设计等相关行业从业人员的指导用书。