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关键词： 装配式   预制阳台   安装   有限元分析   施工技术  

摘要： 针对超大体量装配式预制阳台施工过程中采用传统起吊及转运工具易产生裂缝、现场吊装施工效率低、与现浇部分连接节点复杂等问题,通过对设计、生产运输、安装施工等全过程进行研究,运用ABAQUS有限元软件分析产生质量裂缝的原因。结果表明,超大预制阳台施工过程中严格控制运输存放方式,增加支撑架与阳台板之间接触面,阳台板配筋间距150mm,可以解决超大体量装配式预制阳台生产及安装施工技术问题,提高预制阳台工程质量、提升装配式建筑形象、缩短工期。

关键词： Chemotherapy  

摘要： Purpose: Primary mediastinal B cell lymphoma (PMBCL) is a highly curable subtype of non-Hodgkin lymphoma that is diagnosed predominantly in adolescents and young adults. Consequently, long-term treatment-related morbidity is critical to consider when devising treatment strategies that include different chemoimmunotherapy strategies with or without radiation therapy. Furthermore, adaptive approaches using the end-of-chemotherapy (EOC) positron emission tomography (PET)/computed tomography (CT) scanning may help to determine which patients may benefit from additional therapies. We aimed to develop evidence-based guidelines for treating these patients. Methods and Materials: We conducted a systematic review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline using the PubMed database. The ARS expert committee, composed of radiation oncologists, hematologists, and pediatric oncologists, developed consensus guidelines using the modified Delphi framework. Results: Nine studies met the full criteria for inclusion based on reporting outcomes on patients with primary mediastinal B cell lymphoma with EOC PET/CT response scored with the 5-point Deauville scale. These studies formed the evidence for these guidelines in managing patients with PMBCL according to the EOC PET response, including after a 5-point Deauville scale of 1 to 3, 4, or 5, and for patients with relapsed and refractory disease. The expert group also developed guidance on radiation simulation, treatment planning, and plan evaluation based on expert opinion. Conclusions: Various treatment approaches exist in the management of PMBCL, including different chemoimmunotherapy regimens, the use of consolidative radiation therapy, and adaptive approaches based on EOC PET/CT response. These guidelines can be used by practitioners to provide appropriate treatment according to different disease scenarios. (c) 2021 Elsevier Inc. All rights reserved.

关键词： 功能分区   永定河流域   生态修复  

摘要： 划定流域内各类河流河段的功能,明确河段治理、开发和保护的功能定位,是对流域系统规划和综合治理的首要工作。提出一种基于流域尺度的河流功能区划方法,首先明确了功能区划的定位原则,其次分析流域内河段的生态环境功能,接着明确流域内河段的社会服务功能定位,最后将流域内河段划分为公共活动段、生活服务段、文化风貌段、郊区休闲段、农林保育段、生态观光段六类分段,并以永定河流域为例,该方法以期为后续流域综合生态修复提供指导。

关键词： 土木结构设计   解决措施   图纸设计   伸缩缝   地梁  

摘要： 于建筑项目而言,建筑结构对整个工程的质量和性能起着决定性的作用,而想要设计出安全性高、性能高的土木工程项目,建筑结构设计更是重中之重。目前,尽管我国土木工程建筑已经取得了较大进步,技术水平、设计水平也在不断提升,但土木工程建筑结构设计仍然存在着很多问题,而这会直接影响到整个项目的建筑质量、安全及使用性能。因此,我国需要对其进行深入分析,并采取有效的解决方式,从而全面提升土木工程的设计水平,以保障建筑结构的安全性、稳定性。

关键词： 道路桥梁   伸缩缝   施工技术  

摘要： 伸缩缝施工是道路桥梁工程的重要组成部分,做好这一环节的施工质量控制对提高整个项目的施工质量具有重要作用。伸缩缝施工技术不过关,不仅会影响工程的整体,还会存在很多致命的安全隐患。道路桥梁施工中,伸缩缝施工技术关系到桥梁变形。合理研究道路桥梁伸缩缝施工技术,不仅能避免发生裂缝现象,还能从根本上提高道路桥梁工程的可靠性和安全性。本文对市政道路桥梁工程伸缩缝施工技术进行分析,以供参考。

关键词： 高速公路   双连拱隧道   中隔墙   施工技术  

摘要： 以某高速公路中的隧道工程为例,分析了双连拱隧道中隔墙施工技术,包括控制测量、锚杆超前支护、开挖中导坑等内容。分析结果表明,在双连拱隧道中隔墙施工时,要做好控制测量和超前支护工作并开挖中导坑。同时,施工中隔墙的过程中,要控制好浇筑和振捣工序,保证施工质量,做好防排水措施,避免渗水对隔墙造成不利影响。

关键词： 高职院校   生源多元化   分层分类教学  

摘要： 自2019年高职百万扩招开始,高职院校生源更加多元化。来自不同渠道的学生,层次不一、基础不同、发展需求不一致、个体差异很大。单一的人才培养模式难以满足多元化生源的需求。在此背景下,通过学情分析,开展生源精准分层分类、全面的专业指导、科学制定人才培养方案、建设分层分类课程体系、分步实施分层分类教学等方面的研究,制定了各项保障措施以探索高适用性的分层分类教学模式。

关键词： 城市隧道   防水   混凝土   沉降缝  

摘要： 近年来,随着人口聚集、车辆的增多、城镇化的快速发展,城市隧道在道路交通中广泛应用,有效地缓解了交通压力。城市隧道结构设计使用年限一般为100年,因此对于防水工程的可靠性和耐久性等都提出了较高的要求,以防止隧道渗水漏水状况的发生,确保地下隧道的运行安全。

关键词： 土工复合膨润土防水毯(GCL)   搭接   渗透系数   膨润土   竖向阻隔墙  

摘要： 土工复合膨润土防水毯(geosynthetic clay liners,简称GCLs)在污染场地竖向阻隔墙中应用是一项新技术,通过防水毯相邻幅间搭接区域土工织物的绕渗控制是该技术关键点之一,目前尚缺乏可靠的试验数据支撑。研制了尺寸为1 200 mm×700 mm×700 mm的搭接渗透仪器,在1 m水头差下开展了5级压力(10、25、50、100、150 kPa)下的GCL搭接渗透试验,测量了含500mm搭接区的GCL渗流通量,探究了侧向压力和搭接区是否涂抹膨润土膏对等效渗透系数的影响。试验结果表明:(1)GCL搭接区在渗透初期存在明确的绕流现象,由于绕渗的存在,GCL搭接区域的等效渗透系数ko比完整GCL渗透系数大,搭接区未涂抹膨润土膏时,在低压力(p=10 kPa)作用下前者是后者的5.6倍。(2)搭接区域等效渗透系数随侧向压力增大而减小,在搭接区未涂抹膨润土膏和低压力(p=10 kPa)作用下,搭接区域等效渗透系数ko等于2.27×10^(-8) cm/s,当侧向压力达到100k Pa后,等效渗透系数ko降低至5.93×10^(-9)cm/s。(3)搭接区涂抹膨润土膏能有效提高防渗性能,在各级侧向压力下,GCL搭接区域等效渗透系数ko均低于未涂抹膨润土膏时的,且在高压力状态下(p=150k Pa),ko值降低至5.15×10^(-10) cm/s。

关键词： Arsenic trioxide   Red blood cells   Methylated arsenic   HPLC-HG-AFS  

摘要： Background: Arsenic trioxide (ATO) has been successfully applied in the treatment of acute promyelocytic leukemia (APL). Arsenic metabolites including inorganic arsenic and methylated arsenic could lead to different toxicity and curative effect. This study aims to establish a method to determine arsenic species in red blood cells (RBCs), clarify the distribution characteristics of arsenic species in RBCs. Methods: Steady state blood samples were collected from 97 APL patients. H2O2 and HClO4 were used to release the hemoglobin bounding arsenic and precipitate protein. Arsenite (iAs(III)), arsenate (iAs(V)), monomethylarsonic acid (MMA(V)) and dimethylarsinic acid (DMA(V)) in plasma and RBCs were detected by HPLC-HG-AFS. Free and bound arsenic species in RBCs were separated by 30 kDa molecular mass cutoff filters and determined to evaluate hemoglobin binding capacity of different arsenic species. Results: The method was validated with accuracy ranged from 84.75% to 104.13%. Arsenic species in RBCs followed the trend iAs > MMA > DMA (p < 0.01), while the concentration of DMA was significantly higher than iAs and MMA in plasma (p < 0.01). The correlation between iAs concentration in plasma and corresponding RBCs arsenic level was weak. And the concentrations of DMA and MMA in plasma were moderately positive correlated with those in RBCs. Hemoglobin-binding ratios of iAs, MMA and DMA were all over 70 %. Conclusions: In this study, we provided a reliable method to determine arsenic species in RBCs of APL patients treated with ATO by HPLC-HG-AFS. It was confirmed that the concentration of DMA is the highest in plasma, while MMA is the most predominant methylated arsenic in RBCs. High affinity of MMA with human Hb was responsible for the accumulation of arsenic in RBCs of APL patients. (C) 2021 Elsevier B.V. All rights reserved.