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关键词： 背书   栏杆   阳台  

摘要： 爷爷奶奶睡了,整个镇子上的人都睡了,这会儿出来活动的就只有老鼠了。小老鼠起初还有所忌惮,在栏杆的拐角处探头探脑,不敢出来,默默地在那儿守着,大概是等我离开。最后,它终于等得不耐烦了,大摇大摆地走上阳台,吱吱吱,吱吱吱,比我背书还起劲呢,似乎在嘲笑我。

摘要： Purpose/Objective(s) The 8th AJCC TNM staging system has re-defined stage IB NSCLC as tumor size of 3-4cm (including 4cm) and negative lymph node. The efficacy of adjuvant chemotherapy after surgical resection still remains controversial, and adjuvant chemotherapy is not recommended as regular treatment for stage IB NSCLC. Here we aimed to access the efficacy of adjuvant chemotherapy after surgical resection in stage IB NSCLC patients, and identify the potential high-risk factors associated with the efficacy of adjuvant chemotherapy. Materials/Methods Resected NSCLC patients with 3cm < tumor size≤4cm and negative lymph node diagnosed from 2009 to 2015 were retrieved from the SEER database (Surveillance, Epidemiology, and End Results Program). Age, gender, tumor size, histologic type, differentiation, pleural invasion, adjuvant chemotherapy or not, and surgery type of patients were collected. The Kaplan-Meier and log rank test were used to perform univariate survival analysis. Cox proportional hazards regression models was used to evaluate the association of high-risk features with survival. STATA software was used for data sorting and statistical analyses. Results A total of 3236 operable IB NSCLC were enrolled in this study, in which 395(12.21%) patients received adjuvant chemotherapy and 2841 (87.79%) not. Univariate and multivariate analyses showed that, age > 70 (HR, 1.88; P < 0.0001), male (HR, 1.32; P  = 0.004), poor differentiation (HR = 1.35; P  = 0.002) and wedge resection (HR, 1.68; P < 0.0001) were independent risk factors for overall survival (OS) of IB NSCLC patient. Notably, adjuvant chemotherapy did not affect the overall survival (OS) of patients with IB NSCLC (HR, 0.86; 95% CI, 0.70 to 1.08; P  = 0.20), and the 5-year OS were 61.31% and 65.54% in observation group and adjuvant group, respectively. To further identify the patients with high-risk factors who might benefit from adjuvant chemotherapy, subgroup analysis was performed and the results indi

摘要： Purpose/Objective(s) There is controversy about the need to target the mucosa of the larynx and hypopharynx during radiotherapy (RT) for squamous cell carcinoma of unknown primary site (SCCA-UP). By 1997, the policy in our department was to target only the oropharynx and nasopharynx in patients with SCCA-UP metastatic to the level II cervical nodes. The purpose of this study is to report the rate of cancer recurrence in the larynx or hypopharynx using an approach that excluded these areas from the RT target volumes. Materials/Methods We reviewed the medical records of patients who met the following inclusion criteria: received RT in our department for SCCA-UP between January 1, 1997, and December 31, 2019; no history of surgery that could disrupt the cervical lymphatics; predominant adenopathy in level IIA; and neck stage N1-2c. We excluded N3 because the incidental dose to the larynx and hypopharynx is usually high in patients with a > 6-cm nodal conglomerate. We calculated the following from the date of the last RT fraction: mucosal control to the date of first recurrence in a mucosal site in the head and neck; regional control with or without distant control to the date of first recurrence in ipsilateral or contralateral neck nodes with or without distant disease; distant control to the date of first documented metastatic lesion most likely originating from SCCA-UP; relapse-free survival to the date of recurrent disease at any site or death; cause-specific survival to the date of death due to SCCA-UP; and overall survival to the date of death from any cause. Results The study population included 50 patients with a median follow-up after RT of 7.1 years. No patient developed recurrent cancer in a mucosal site (0/50), 2% (1/50) developed a neck recurrence in a high-dose area with synchronous distant metastases, and 2% (1/50) developed distant metastases with no evidence of local or regional recurrence. At most recent follow-up, 70% (35/50) of patients were alive wi

关键词： 房屋建筑结构   抗震设计   防震缝  

摘要： 文章阐述了房屋建筑结构抗震设计的重要意义,提出了房屋建筑结构的抗震设计策略,包括严格按照抗震标准开展设计、科学设计防震缝、合理设计建筑物的高宽、规范建筑物架构、做好建筑物墙体设计、选择高质量的建筑结构材料。

关键词： 伸缩装置   典型病害   成因分析   防治技术   处理措施   行车安全  

摘要： 根据桥梁伸缩缝典型病害的调查,分析研究了病害成因,针对桥梁伸缩缝典型病害提出了防治技术和处理措施,以保证城市桥梁全寿命周期内桥梁伸缩缝正常工作,保证行车安全,行车舒适,提升人民幸福感。

关键词： lymphoma   retroperitoneal   features  

摘要： Due to a high degree of heterogeneity,different primary sites of diffuse large B-cell lymphoma(DLBCL)will have different clinical features and *** Revised European-American Lymphoma(REAL)classification emphasizes that knowledge of the primary site of the process is of high diagnostic value for unusual *** large B-cell lymphoma primarily located in the retroperitoneum(PRLBCL)has been the subject of occasional reports.[1,2]The retroperitoneal space is large,embedded in a meshwork of loose connective tissue,allowing both primary and metastatic tumors to grow silently before clinical symptoms appear,therefore tumors in the retroperitoneum are often *** is difficult to distinguish them from retroperitoneal lymphoma,and solid tumors such as gastrointestinal stromal ones and neurofibromas.[3]This study retrospectively analyzed PRLBCLs in our hospital to bette。

关键词： 建筑设计师   建筑实体   公共区域   层次结构   House   阳台   庭院   现代需求  

摘要： Gadi House位于印度塔莱加奥恩达巴德,承载着Maratha Sardars家族的荣誉和血统。他们希望这座新房子成为他们社会地位屹立不倒的形象。建筑设计师试图在这里找到传统与现代之间的关系。房屋命名为“Gadi”(土地堡垒),建筑面积总共1.2英亩(约4856m^(2))。外面有厚厚的壁垒,就像一座小城堡。内部的庭院、阳台和公共区域有着开放、半开放和封闭的层次结构。设计师重新利用这些元素,组合成一个满足了现代需求和吸收了优良传统的建筑实体。

摘要： Purpose/Objective(s) Previous studies have shown a detrimental effect of postoperative radiation (PORT) in pN1 NSCLC patients after R0 surgery. High lymph node ratio (LNR = number of positive lymph nodes in the resected specimen/number of total lymph nodes resected) has been shown to correlate with worse outcomes. We hypothesize that PORT can improve survival outcomes in pN1 NSCLC patients with high LNR after R0 surgery. Materials/Methods The National Cancer Database was queried for cases of lung cancer from 2004-2016. Patients without neoadjuvant treatment, with at least a lobectomy with resection of at least 10 lymph nodes, with pN1 disease, with histology of squamous cell carcinoma, adenocarcinoma, adenosquamous carcinoma and large cell carcinoma were included. Exclusion criteria were neoadjuvant therapy, lack of pathological confirmation or lack of information about chemotherapy and metastatic disease. For patients with PORT, RT was directed to thorax with dose≥30Gy. Log-rank test and Cox proportional hazards models were used to compare survival adjusted for age, sex, CCI, pT, grade, chemotherapy, LNR, and PORT. Predictors for overall survival (OS) were identified. Results Among 13742 patients, 12542 (91.3%) did not have PORT, and 1200 (8.7%) had PORT. Median follow up was over 5 years. For years of 2004-2010 and 2011-2016, PORT was given to 8% (413 out of 5132) and 5.5% (423 out of 7622) of patients after R0 resection, respectively. PORT was given to 36.8% and 6.55% patients with non-R0 and R0 resection, respectively (P < 0.001). PORT was given to 11.6% and 3.37% of patients with and without adjuvant chemotherapy, respectively (P < 0.001). The average LNR for patients with and without PORT were 0.2 and 0.14 (P < 0.001), respectively. In multivariate analysis (MVA) of patients with R0 resection, predictors of OS were listed in Table 1. In patients with intermediate LNR (15-29%), PORT was marginally correlated with better OS (HR, 0.80, P  = 0.07). In patients wit