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关键词： 物理化学   课程思政   人生观   价值观   世界观  

摘要： 本校《物理化学》课程主要面向给水排水科学工程专业的本科生,课程理论性较强,公式推导过程难,公式多,学生容易产生厌学心理。因此,在《物理化学》课程的教学过程中对学生进行适度的思想政治教育。使学生以书中的化学家物理学家为精神榜样,树立正确的人生观、价值观、世界观。

关键词： 表面活性剂   临界胶束浓度   拟相分离模型   热力学   活化能  

摘要： 通过电导法考查温度和盐浓度对十二烷基硫酸钠(SDS)临界胶束浓度(CMC)的影响,研究表面活性剂形成胶束过程的物理化学性质。根据拟相分离模型求得胶束化热力学函数,并讨论体系电导活化能随温度和SDS浓度变化关系。结果表明:SDS的CMC随温度升高而增加,随氯化钠浓度增大而减小。在热力学上SDS在水溶液中形成胶束是一个自发、放热、熵增的过程;在动力学上,SDS溶液电导率与温度关系符合Arrhenius公式,通过电导活化能信息可揭示离子型表面活性剂形成胶束的机理特征。

关键词： 物理化学   科研应用   光催化   润湿方程   量子点  

摘要： 针对物理化学教学内容基础性和理论性强的问题,作者在课程中将科研应用与课程内容结合,使学生认识到基本理论的重要性,提高对课程的学习兴趣,从而更好地掌握课程中的基本概念和规律。这种教学方式同时拓宽了学生的视野,培养了学生的创新科研意识。

关键词： Rosa roxburghii Trat t   Pyracantha fortuneana   Rosa laevigata Michx   Rosa sterilis   Guinong 5  

摘要： In China, three Rosaceae fruits with distinctive flavours and functions have recently been transformed from edible plants into standardised juice or beverage products. To enhance the development of these fruit products, the results and conclusions from various investigations of the chemical and biological properties of fruits should be summarised. Based on industrial advances, there ar e sti l l some limitation in the research and development of these fruit products that need to be addressed. Therefore, in this report, we provided a comprehensive and rigorous review to summarise critical data from phytochemical and biological investigations and from flavou r profiles and industrial development of these fruit products. Ou r goal is to provide insights into recent research findings in order to advance studies and developments of products of these flavourf u l fruits from a reasonable perspective.

关键词： Cyclosporine A   Amorphous solid dispersion   Poor water solubility   Hot melt extrusion   Bioavailability  

摘要： In this study, the amorphous solid dispersions of cyclosporine A (CsA-ASDs) were prepared by hot melt extrusion (HME) with PVP K12 as carrier to improve the oral bioavailability of CsA. The polymers were screened by solubilization and recrystallization inhibition experiments, then the CsA-ASDs were prepared with optimized technological parameters and characterized on thermodynamics and morphology. The results showed that CsA was dispersed among PVP K12 as amorphous form in CsA-ASDs, and the infrared spectrum testified that there was possible hydrogen bond interaction between CsA and PVP K12. The in vivo pharmacokinetics of CsA formulations in rats were analyzed via LC-MS. The AUC of CsA-ASD tablets increased by 7.3 times compared to CsA bulk powder and 3.1 times in contrast to CsA-PM tablets, respectively. The experiment proved that CsA-ASD tablets significantly improved the dissolution and absorption of the drug. This study had a reference value for the bioavailability improvement of oral CsA preparations.

关键词： 物理化学   自拟试题   学习主动性  

摘要： 为了促进学生对物理化学知识的掌握与理解,在物理化学教学中设计自拟试题环节,给学生布置"自己拟定一套物理化学试题(含答案)"的任务并对学生的反馈进行总结和点评。旨在让学生通过此项训练,将所学知识点系统的总结与梳理,并且更全面深入的加强对知识的理解,达到融会贯通的效果,最终有望促进物理化学的学习。

关键词： 物理化学实验   教学改革  

摘要： 结合物理化学实验课程特点和地方应用型本科院校人才培养要求,本文针对当前物理化学实验教学过程中存在的问题,以位于长江三角洲地区的应用型本科院校常州工学院的化学工程与工艺专业为例,探讨了物理化学实验课程的教学改革,并提出了具体改革举措。

关键词： 疫情防控常态化   新工科院校   物理化学   教学改革   线上和线下教学  

摘要： 疫情防控常态化背景下,高校随时都可能面临无法开展常规课堂教学的困境。如何提高课程线上和线下教师教学水平,是新形势下建设高水平地方应用型大学学科建设、专业建设和学生培养亟需解决的重要问题。本文结合新工科院校自身特点,以福建工程学院为例,通过剖析物理化学线上和线下教学存在的问题,总结和改进课程教学模式和教学方法,提升疫情防控常态化背景下新工科院校物理化学的教学水平,提高学生综合素养。

关键词： Nerve tissue engineering   Hydroxyapatite   Electrospinning  

摘要： The ability to mimic the extracellular matrix (ECM) by electrospun fibers has opened new practical ways in nerve tissue engineering. In the current research, polycaprolactone (PCL)/poly(glycerol sebacate) (PGS) scaffold containing 5, 10, and 15 wt% hydroxyapatite (HAp) particles were electrospinned. The morphology, surface contact angle, mechanical properties, in vitro degradation behavior, and water uptake of the PCL/PGS/HAp fibers were studied. The viability and adhesion of the rat pheochromocytoma cell line (PC12) on each scaffold were investigated using MTT assay and scanning electron microscope (SEM), respectively. SEM images revealed that the fibers were uniform and aligned in general, while by increasing the HAp particles loading from 0 to 15%, the fiber diameter decreased from 831 to 382 nm. According to transmission electron microscopy (TEM) images, needle-like HAp particles were distributed along the fibers. Fourier-transform infrared spectroscopy (FTIR) and X-ray analyses confirmed the chemical interactions between PCL, PGS, and HAp. Young's modulus of all fibers was about 0.16-0.3 MPa, which is practically suitable for nerve tissue engineering. HAp particles displayed a positive effect on PC12 viability and adhesion. To conclude, the results suggested that electrospun PCL/PGS/HAp fibers can be a promising biodegradable scaffold for serving in nerve tissue engineering.

关键词： 教育技术装备   实验教师   党支部书记   生物科学   河南省安阳市   教学观摩课   铁佛寺   物理化学  

摘要： 本刊讯2021年10月22日,河南省安阳市殷都区教育技术装备中心在安阳市铁佛寺小学举行"2021年秋季殷都区实验教学观摩课"活动。安阳市教育技术装备中心办公室主任刘海卿,安阳市第九中学党支部书记、校长焦胜利,殷都区教育技术装备中心主任郑启风出席本次活动。活动由殷都区教育技术装备中心副主任李建主持。来自全区的120名一线物理化学生物科学实验教师参加了此次活动。