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关键词： 实验课   网络平台   建设  

摘要： 实验室是实验教学的主要场所,近年来,改革传统的实验课教学模式,建设实验课网络教学平台已成为提高实验课教学质量、培养高素质人才的重要途径。针对现状,研究开发实验室网络平台,弥补了传统实验教学的不足,为实验教学提供了有力的支撑。

关键词： 光散射探针   蛋白质   核酸   金属离子   检出限  

摘要： 文章综述了共振光散射探针的应用技术与原理,探讨了探针类化合物在蛋白质、核酸及痕量金属离子的检测方法及影响因素,为蛋白质和核酸分析方法的建立、螺旋结构及生物化学的研究提供思路,为提升金属离子检测限提供方法和依据.

关键词： 分析化学家   中国化学会   基础研究   科研机构   企事业单位   军事医学科学院   日至   大连化物所   化学研究所   方群  

摘要： 2015年5月9日至11日,由中国化学会和国家自然科学基金委主办、华中师范大学承办的第十二届全国分析化学年会在武汉召开。来自全国高等院校、科研机构、企事业单位的近2200名专家学者出席了会议。在大会开幕式上,分别颁发了＂分析化学基础研究梁树权奖＂、＂中国女分析化学家奖＂和＂青年分析化学家奖＂。

关键词： 分析化学   镍释放量   石墨炉原子吸收光谱法   人工汗液   不确定度  

摘要： 镍广泛应用于珠宝首饰材料中，但它也是一种潜在的致敏元素，欧洲和中国均已发布强制性标准来控制首饰中镍释放对人体健康带来的风险。针对欧盟最新版标准EN1811：2011与现行的中国国家标准GB／T19719—2005存在的主要区别：人工汗液成分不同和测试结果表达方式不同，用石墨炉原子吸收光谱仪测定了按该两个标准检测的22件18K金样品的测试液。研究表明，欧盟标准用苛性钠溶液替代稀氨水调节人工汗液的pH值，汗液的pH值在镍释放过程中变化较小，检测数据具有较低的不确定度和相对标准偏差，即数据更稳定；欧盟标准中用测定不确定度来修正镍释放量d，检测结果偏高，说明该标准更严格，更能把好含镍饰品的质量关，减少镍元素对人体伤害。

关键词： photography   imagination   colorimetry   digital photography   mobile phone   RGB   CMYK   photometry   diagnosis   acetylcholinesterase   butyrylcholinesterase   naked eye detection  

摘要： Smartphones are popular devices frequently equipped with sensitive sensors and great computational ability. Despite the widespread availability of smartphones, practical uses in analytical chemistry are limited, though some papers have proposed promising applications. In the present paper, a smartphone is used as a tool for the determination of cholinesterasemia i.e., the determination of a biochemical marker butyrylcholinesterase (BChE). The work should demonstrate suitability of a smartphone-integrated camera for analytical purposes. Paper strips soaked with indoxylacetate were used for the determination of BChE activity, while the standard Ellman's assay was used as a reference measurement. In the smartphone-based assay, BChE converted indoxylacetate to indigo blue and coloration was photographed using the phone's integrated camera. A RGB color model was analyzed and color values for the individual color channels were determined. The assay was verified using plasma samples and samples containing pure BChE, and validated using Ellmans's assay. The smartphone assay was proved to be reliable and applicable for routine diagnoses where BChE serves as a marker (liver function tests;some poisonings, etc.). It can be concluded that the assay is expected to be of practical applicability because of the results' relevance.

关键词： green chemistry metrics   green analytical chemistry metrics   environmental impact   E-Factor   atom economy   eco-footprint   Eco-Scale   EATOS  

摘要： The concept of green chemistry is widely recognized in chemical laboratories. To properly measure an environmental impact of chemical processes, dedicated assessment tools are required. This paper summarizes the current state of knowledge in the field of development of green chemistry and green analytical chemistry metrics. The diverse methods used for evaluation of the greenness of organic synthesis, such as eco-footprint, E-Factor, EATOS, and Eco-Scale are described. Both the well-established and recently developed green analytical chemistry metrics, including NEMI labeling and analytical Eco-scale, are presented. Additionally, this paper focuses on the possibility of the use of multivariate statistics in evaluation of environmental impact of analytical procedures. All the above metrics are compared and discussed in terms of their advantages and disadvantages. The current needs and future perspectives in green chemistry metrics are also discussed.

关键词： ANALYTICAL chemistry   MASS spectrometry   BIBLIOMETRICS   CHEMICAL engineering   CHEMICALS  

摘要： In this Feature we use automatic bibliometric mapping tools to visualize the history of analytical chemistry from the 1920s until the present. In particular, we have focused on the application of mass spectrometry in different fields. The analysis shows major shifts in research focus and use of mass spectrometry. We conclude by discussing the application of bibliometric mapping and visualization tools in analytical chemists’ *** J. F. Waaijer ^*? and Magnus Palmblad ^{? ?} Centre for Science and Technology Studies, Faculty of Social and Behavioural Sciences, Leiden University, P.O. Box 905, 2300 AX Leiden, The Netherlands^? Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The NetherlandsAnal. Chem., 2015, 87 (9), pp 4588-4596DOI: 10.1021/ac5040314Publication Date (Web): March 6, 2015Copyright ? 2015 American Chemical Society*Phone: +31 71 527 6072. Fax: +31 527 3911. E-mail: ***@*** Cathelijn Waaijer works as a doctoral researcher at the Centre for Science and Technology Studies at Leiden University. She did her ***. in Biomedical Sciences and did a research project on the mass spectrometric analysis of cartilage tumors at the Leiden University Medical Center (LUMC).Biography Magnus Palmblad is Associate Professor at the LUMC Center for Proteomics and Metabolomics specializing in clinical applications of and informatics solutions for mass spectrometry based proteomics.