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关键词： Organic Chemistry   Drugs/Pharmaceuticals   Medicinal Chemistry   Laboratory Instruction  

摘要： Modern, quality education for health sciences is vital in developing and strengthening the health systems of countries in southern Africa. Medicine, pharmacy, and other disciplines in the region typically admit high school graduates who tend to undertake a science foundation in the first years of study. We report a new resource for improving the organic chemistry training of first year health science students at the University of Namibia. Short prelab videos were produced and made available for students prior to laboratories. This new resource was evaluated through an online survey tool, and responses were generally positive. A number of improvements were identified to improve the resource and develop further prelab videos for other modules taught.

关键词： Second-Year Undergraduate   Organic Chemistry   Laboratory Instruction   Molecular Modeling   Synthesis   Thermodynamics   Inquiry-Based/Discovery Learning   Computer-Based Learning   Hands-On Learning/Manipulatives  

摘要： A laboratory experiment was developed that connects the interpretation of computer-generated models to the self-assembly of macrocycles. Students compare the reactions of terephthalaldehyde and isophthalaldehyde by reacting each with (R,R)-(-)-1,2-diaminocyclohexane. These isomeric systems serve as the foundation for a discussion about the impact of entropy and enthalpy on macrocycle formation. This experiment requires students to use multiple data sources to develop evidence-based explanations about the impact of the starting-material geometry on macrocyclization. Results from laboratory implementation indicate that a majority of students were able to successfully demonstrate competency of the learning goals.

关键词： 有机化学   化学实验   高等学校   教材  

ISBN: (纸本)9787548237228

摘要： 本教材的内容包括有机化学实验的安全知识和基础知识、天然有机化学实验、复杂有机物合成实验、有机化合物结构解析基础理论和复杂有机化合物结构解析实例，让学生较全面、深入地掌握有机化学实验方法和技能。本教材注重实验过程中的安全防护，部分内容采用微量、半微量的手段进行实验；结构解析部分选取部分国际性学术期刊的复杂天然产物作为实例，试图从不同角度，使用不同的方法来介绍复杂结构的有机物的结构解析，以期学生能真正学会结构解析相关知识。

关键词： 翻转课堂   有机化学实验   实验教学   教学改革   中医药思维  

摘要： 传统实验教学多为灌输式模式,学生学习自主性不足,学习兴趣不高。基于传统实验教学模式中存在的一些弊病,尝试采用“翻转课堂”模式应用于中医药院校有机化学实验教学,以期提高教学质量,并为有机化学实验教学改革提供一种新的尝试。“翻转课堂”教学模式打破了传统的教学方式,使教师灌输知识变为学生自主学习,实现了从被动学习变为主动吸纳。应用该模式教学有利于培养学生的自主学习能力和创造性思维,教学效果明显提升。

关键词： 有机化学   高分子材料   合作   应用  

摘要： 随着我国科学技术水平的不断提升,有机化学作为一种应用广泛的高分子合成材料,因其具有性能好、使用方便、自重轻等特点,受到了众多行业的青睐。近年来,我国在有机化学方面的研究力度不断加大,有机化学被应用在高分子材料合成中,并且取得了显著的效果。基于此,本文简要介绍了有机化学合成材料,并且重点分析了有机化学在高分子材料合成中的应用方法,进一步延伸阐述了高分子材料的绿色可持续发展目标,以供同行业人士参考。

关键词： 有机化学   教学方法   主线法   案例法   多元化  

摘要： 有机化学作为高职药学专业四大化学基础课程之一,课程内容丰富多样,在生命科学及新药研发等诸多学科领域中均有重要作用.有机化学反应机理变化多样,学生往往感觉理论性强、内容复杂且枯燥,时间一长导致学习兴趣下降,严重影响教学效果.对教师而言,在完成教学目标、确保教学质量的同时也不能忽视对学生综合素质的培养和创新能力的提高,因此,有机化学教学改革已然是势在必行.本文结合我院在有机化学日常教学过程中的体会和一些尝试,探讨高职有机化学课程教学改革与实践方法,以便能更好的适应当前学科教学发展趋势,培养出更优秀的高职应用型人才.

关键词： Stereochemistry  

摘要： Glycals, 1,2-unsaturated sugar derivatives, are versatile starting materials for the synthesis of natural products and the generation of novel structural features in Diversity Oriented Synthesis (DOS). The versatility of glycals in synthesis emanates, among others, from the presence of the ring oxygen and the enol-ether type unsaturation, the different types of stable conformations they can adopt depending on the nature of the protecting groups present and the ease with which the protecting groups of the three hydroxy groups could be tailored to suite for a desired manipulation. This review summarizes the literature on the different transformations of the endo glycals into biologically relevant compounds such as chromans, thiochromans, chromenes, thiochromenes, peptidomimetics, bridged benzopyrans etc., as well as on the use of glycals as chiral building blocks for the synthesis of various natural products such as aspicilin, reblastatin, diospongins, decytospolides, osmundalactones, paclitaxel, isatisine, D-fagomine, and spliceostatin, reported post 2014.