关键词： 网络平台   多模式联合教学   神经病学  

摘要： 目的:探讨网络平台下多模式联合教学法在神经病学教学中的应用效果。方法:实验组学生172名和对照组学生165名,实验组学生缩短传统教学的时间,联合以下4种方法:PBL教学、CBL教学(案例教学法)、微信教学、网络平台教学;对照组学生按照传统讲授模式,通过多媒体PPT方式讲授基础理论课的内容,完成基础理论的教学及实践操作;教学活动结束后,将实验组及对照组两组同学统一进行考试,记录学生成绩并发放满意度调查表。结果:通过比较,实验组学生成绩明显高于对照组(分别为P=0.021,P<0.05);实验组学生满意度高于对照组,(P=0.040,P<0.05)。结论:网络平台下多模式联合教学法相对于传统教学模式,更有助于提高学生综合成绩,得到学生的认可。

关键词： translation   microsatellite repeat diseases   RAN translation   toxicity   mechanism   therapy  

摘要： Microsatellite mutations involving the expansion of tri-, tetra-, penta-, or hexanucleotide repeats cause more than 40 different neurological disorders. Although, traditionally, the position of the repeat within or outside of an open reading frame has been used to focus research on disease mechanisms involving protein loss of function, protein gain of function, or RNA gain of function, the discoveries of bidirectional transcription and repeat-associated non- ATG (RAN) have blurred these distinctions. Here we review what is known about RAN proteins in disease, the mechanisms by which they are produced, and the novel therapeutic opportunities they provide.

摘要： 《临床神经病学杂志》系国家级神经病学专业性学术期刊。国内统一刊号CN 32-1337/R, 国际标准刊号ISSN 1004-1648。曾荣获第二届全国优秀科技期刊奖及连续多次江苏省优秀期刊奖,并已入选中文核心期刊及中国科技核心期刊。2005年、2006年先后被美国化学文摘(CA)、俄罗斯文摘杂志(РЖ)、波兰哥白尼索引(IC)以及美国《乌利希国际期刊指南》四大数据库收录。本刊始终坚持"面向临床、面向基层、注重实用"的办刊宗旨,多年来已成

关键词： 神经病学教育   专业课教育   思政教育  

摘要： 探索思想政治教育在神经病学专业课教学中的应用方法与策略。分析高校思政教育进入专业课的意义,以及思政教育融入神经病学教学之中的特点,介绍思政教育融入神经病学教学的具体实践方法及意义,发现把思想政治工作贯穿神经病学教育教学全过程,有助于专业课程教学与思想政治理论课同向同行,形成协同效应;有助于提高学生专业自信,激发学习热情;有助于认同中华文化,对坚持不懈的培育和弘扬社会主义核心价值观。

关键词： MOTOR learning   SCHIZOPHRENICS   BIPOLAR disorder  

关键词： PBL教学法   神经病学   教学   科研训练  

摘要： 目的是研究PBL教学法在神经病学教学及科研训练中的应用。方法是选择2016年9月-2019年5月的72名医学生作为研究对象。按照随机原则分为观察组和对照组,每组各36名。对照组采用传统带教方法,观察组给予PBL教学法,观察对医学生教学及科研训练效果。结果是观察组病例分析评分为(86.11±2.03) 分,对照组病例评分为(83.61±1.92)分,观察组病例分析成绩高于对照组,差异具有统计学意义(P <0.05);观察组自主创新课题设计的优良率为(30,83.33%),对照组自主创新课题设计的优良率为(22,66.11%),差异具有统计学意义(P< 0.05)。结论是通过PBL教学法的应用,可以为培养医学生临床思维及科研思维提供一种良好的方式,有利于改善教学质量及教育改革。

关键词： moyamoya disease   psychosis   vascular headache  

摘要： Moyamoya disease (MMD) is a rare arteriopathy associated with cerebral ischemia, due to stenosis or occlusion of the internal carotid artery and its branches and primarily presenting with stroke. However, neuropsychiatric symptoms such as acute psychosis, manic symptoms, attention deficits, and behavioral problems are reported in relation to MMD. We describe here a case of an adult female, who presented with headache, easy irritability, and suspiciousness against family members, inability to identify familiar objects and faces, and inability to perform activities easily done earlier. This case appears informative as the presence and excessive importance given to behavioral symptoms lead to substantial delay in her diagnosis.

关键词： Clinical psychology   Neurosciences   Personality--Psychological aspects   Metacognition   Older people   Nervous system--Diseases   Nervous system--Diseases--Etiology  

摘要： This project consists of three distinct, but sequential studies that explore the psychological factors and neuropathological substrates of metacognition or self-awareness among older adults. Study 1 examines the premorbid, psychological characteristics associated with metamemory—the mainstay of metacognitive research—in a healthy, community-dwelling cohort of older adults. Study 2 builds on these analyses, and examines the psychological characteristics associated with metacognition, more broadly, in a neurologic cohort of older adults with Essential Tremor (ET). Study 3, which utilizes post-mortem evaluations of participants from Study 2, goes beyond premorbid characteristics and examines whether distortions in metacognition are in part attributable to an underlying disease process. Findings demonstrated that psychological characteristics were associated with metacognitive accuracy in a healthy, community-dwelling cohort of older adults, but not among individuals with ET; further, distortions in metacognition among individuals with ET were better attributable to non-ET specific pathologies, such as amyloid β, neurofibrillary tangles, and regional-specific atrophy. This project underscores the importance of employing a biopsychosocial approach to understanding the factors that influence metacognition. Ultimately, by understanding and working effectively with awareness phenomena, there is a strong potential to reduce disability and enhance well-being.

关键词： 对分课堂   案例教学法   神经病学  

摘要： 神经病学是一门综合性学科,负责诊断,治疗,教学,科研和预防的艰巨任务。神经内科也是一门高度复杂的学科,它要求医师具有缜密的临床思维和解决复杂临床问题能力。针对神经病学专业的特点,神经病学教育应注重临床实践,将专业理论融入临床实践,提高学生分析解决复杂临床问题的能力[1]。传统的教学方法侧重于以讲授为主,强调教学大纲和概念的传递。老师讲解理论知识,学生聆听和记笔记,被动地接受知识,学生缺乏发现问题和

关键词： 《临床神经病学杂志》   作者姓名   第一作者   版面费  

摘要： 《临床神经病学杂志》系国家级神经病学专业性学术刊物,由南京医科大学附属脑科医院主办。刊登内容以临床神经病学为主,兼及有关边缘学科。读者对象以从事临床神经病学专业的高、中级人员为主,也可供内科、儿科、眼科、五官科医师参阅。本刊的办刊宗旨是:面向临床,面向基层,注重实用,鼎力于提高我国临床神经科医师的专业理论及诊疗水平。一、本刊设有专家论坛、述评、论著、学术交流、专题笔谈、综述、讲座、临床病理(例)讨论、教学园地、问题解答、临床研究、病例报告、误诊误治、技术改进等栏目,接受全国各地来稿。