关键词： 《中文核心期刊要目总览》   文献计量学   出版周期   神经疾病   研究人员   专家评审   精神病学   神经病学  

摘要： 《中国现代神经疾病杂志》主编:我们谨此郑重通知:依据文献计量学的原理和方法,经研究人员对相关文献的检索、统计和分析,以及学科专家评审,贵刊《中国现代神经疾病杂志》入编《中文核心期刊要目总览》2017年版(即第8版)之"神经病学与精神病学"类的核心期刊。该书由北京大学出版社出版。书中按《中国图书馆分类法》的学科体系,列出了78个学科的核心期刊表,并逐一对核心期刊进行了著录。著录项目包括:题名、并列题名、主办单位、创刊时间、出版周期、学科分类号、ISSN号、CN号、邮发代号、编辑部地址、邮政编码、电话、网址、电子邮箱、内容简介等。

关键词： Ictal asystole   Epilepsy   Pacemaker   Apnea  

摘要： Ictal asystole can appear in patients with focal epilepsy, even in early phases. We present our experience of 7 cases, remarking the electrocardiographic characteristics, the role of apnea, treatment and long-term evolution. Awareness of this entity and collaboration between neurologists and cardiologists are essential for a correct diagnosis and management. (c) 2018 Elsevier B.V. All rights reserved.

关键词： 神经病学   教学改革   微课   翻转课堂  

摘要： 目的探讨利用微课的翻转课堂在神经病学教学中的效果。方法选取湘南学院2014级临床医学专业专升本9～14班共245人为研究对象,根据教学方法的不同进行分组,9～11班为观察组(n=144),12～14班为对照组(n=141)。观察组采用基于微课的翻转课堂教学模式,对照组采取传统授课方式。将两组学生的考核成绩进行比较分析,自制问卷调查观察组学生对基于微课的翻转课堂教学模式的评价情况。结果观察组学生的基础理论知识成绩、病例分析成绩、总成绩均高于对照组(P<0.05),观察组对基于微课的翻转课堂教学模式评价良好。结论在神经病学教学中采用基于微课的翻转课堂教学模式有助于提高教学效果,提升学生的专业素质。

关键词： 以问题为基础学习   床边学习   电子病历   手写病历   神经病学  

摘要： 目的:探讨以问题为基础学习法(PBL)在电子病历(EMR)及手写病历(HMR)模式下对神经科临床思维的教学效果。方法:将93名神经内科实习生随机分为PBL电子病历(PBL-EMR,32人)和手写病历组(PBL-HMR,30人),与床边教学手写病历组(BBL-HMR,31人)对照,分别采用PBL或BBL法带教并比较教学效果。结果:实验后,PBL-EMR和PBL-HMR组实习医生的临床思维(P<0.05)、理论(P<0.01)和总成绩(P<0.01),口试成绩(P <0.05)均明显高于BBL-HMR组;但PBL-EMR和PBL-HMR组间各指标均无明显差异。结论:PBL在EMR和HMR模式下对临床思维的教学效果类似;且优于HMR模式下BBL教学。

关键词： 神经病学   临床   教学   沟通   探索  

摘要： 近年来,医患矛盾已逐渐成为一个社会问题,我国医患矛盾形势越来越严峻,与社会价值观的扭曲、医疗体制机制不完善有密切的联系,而很大一部分则与人文关怀的缺失、医患沟通不到位有关。良好的医患沟通和交流不仅能提升患者满意度和依从性,还能有效避免医患纠纷事件发生。提高临床医师与患者及家属的沟通能力对于构建和谐的医患关系及减少不必要的医疗纠纷具有重要的意义。即将踏上工作岗位的临床医师,在大学理论课期间,只学过医患沟通相关理论知识,缺乏基本的医患沟通能力及技巧。本文结合神经疾病科临床实际,从如何培养一个合格的具备良好医患沟通能力的医师出发,提出更合理化的医学教学方法,希望探索出一套对提高神经疾病科临床医师医患沟通能力有帮助的临床教学方法,将医患沟通纳入常规教学,并推广应用。让学生在掌握理论技能的同时,掌握医患沟通的方法,增强实践性,为临床工作的顺利进行提供保障。

关键词： Leadership   Organized neurosurgery   YNC   Young Neurosurgeons Committee  

摘要： The Young Neurosurgeons Committee, founded in 1991 by Dr. Roberto C. Heros, has been a vital component of the American Association of Neurological Surgeons. It has grown from an opportunity for young neurosurgeons to network with senior neurosurgeons to becoming the major voice of young neurosurgeons and a training ground for the future leaders of organized neurosurgery. The present report has reviewed the leadership involvement of 168 previous Young Neurosurgeons Committee members and briefly highlighted the careers of 4 of these members who have attained leadership positions in neurosurgery.

关键词： attitudes   caring   clinical guidelines   communication   experiences   focus groups   knowledge   nurse   older patients   qualitative approaches  

摘要： Aims and objectives To investigate nurses' experiences of caring for older (65+ years) patients afflicted by delirium in a neurological department. Background Delirium is a frequent, acute and potentially fatal condition. Patients experience delirium as painful and stressful. The literature shows that nursing care is crucial in the prevention and treatment of delirium. The nurses' approach to the patient with delirium is essential for the quality of care provided to the patient. Design A qualitative, exploratory design was used to study the nurses' experiences of caring for patients afflicted by delirium. The study complied with the Consolidated Criteria for Reporting Qualitative Research (COREQ). Methods A total of fourteen nurses participated in three focus groups. The nurses' narratives were used to elucidate their experiences, perceptions, attitudes and views towards the patient with delirium. The texts were analysed using thematic analysis. Results The analysis revealed three themes: The relationship with the patient is challenged, expertise is requested, and barriers to cooperation exist. Conclusions Nurses experienced a relationship with patients with delirium that was influenced by a lack of knowledge about communication with such patients. This resulted in a lack of person-centred care and knowledge about the patient's habitual condition and life story;hence, nurses did not discover the patient's initial delirium. Inadequate and unstructured documentation did the nursing effort initiated late so the patient's delirium was developing. Uncertainty caused lack of dialogue between nurses, which afflicted the partnership and relation between the patient and the nurse. A fast pace workload affected relationships, knowledge, documentation and collaboration. Thus, the person-centred approach to the patient was challenged, which made the provision of professional nursing care difficult. Relevance to clinical practice A continuous focus on patients with delirium, as

关键词： Gaucher   GBA   glucocerebrosidase   neuronopathic   Parkinson  

摘要： The association between Gaucher disease (GD) and Parkinson disease (PD) has been described for almost two decades. In the biallelic state (homozygous or compound heterozygous) mutations in the glucocerebrosidase gene (GBA) may cause GD, in which glucosylceramide, the sphingolipid substrate of the glucocerebrosidase enzyme (GCase), accumulates in visceral organs leading to a number of clinical phenotypes. In the biallelic or heterozygous state, GBA mutations increase the risk for PD. Mutations of the GBA allele are the most significant genetic risk factor for idiopathic PD, found in 5%-20% of idiopathic PD cases depending on ethnicity. The neurological consequences of GBA mutations are reviewed and the proposition that GBA mutations result in a disparate but connected range of clinically and pathologically related neurological features is discussed. The literature relating to the clinical, biochemical and genetic basis of GBA PD, type 1 GD and neuronopathic GD is considered highlighting commonalities and distinctions between them. The evidence for a unifying disease mechanism is considered.

关键词： Cardiac arrest   Prognosis   Risk score   CAHP   OHCA   Cardiopulmonary resuscitation  

摘要： Aim: Several scores are available to predict mortality and neurological outcome in cardiac arrest patients admitted to the intensive care unit (ICU). The aim of the study was to externally validate the prognostic value of four previously published risk scores. Methods: For this observational, single-center study, we prospectively included 349 consecutive adult cardiac arrest patients upon ICU admission. We calculated two cardiac arrest specific risk scores (OHCA and CAHP) and two general severity of illness scores (APACHE II and SAPS II). The primary endpoint was in-hospital mortality. Secondary endpoints were neurological outcome at hospital discharge and 30-day mortality. Results: 170 patients (49%) died until hospital discharge. All scores were independently associated with outcomes in logistic regression analysis and showed acceptable discrimination for in-hospital mortality with highest AUCs of the cardiac arrest specific risk scores (OHCA: 0.80 (95% CI 0.75-0.85) and CAHP: 0.84 (95% CI 0.79-0.88) compared to the severity of illness scores (APACHE II: 0.78 (95% CI 0.73-0.83) and SAPS II: 0.77 (95% CI 0.720.82). Results were robust in subgroup analysis except for worse performance in elderly patients (>75 years) and patients with respiratory cause of cardiac arrest. Results were similar for 30-days mortality and slightly higher for neurological outcome. Conclusions: This study confirms the good prognostic performance of cardiac arrest specific scores to predict mortality and neurological outcomes in cardiac arrest patients. Routine use of OHCA or CAHP score helps to objectively risk stratify these vulnerable patients and thereby may improve therapeutic decisions.

关键词： CX3CL1   Neuroprotective   Neurotoxic   Neuroinflammatory   Neurological disease  

摘要： Fractalkine (CX3C chemokine ligand 1, CX3CL1) is an essential chemokine, for regulating adhesion and chemotaxis through binding to CX3CR1, which plays a critical role in the crosstalk between glial cells and neurons by direct or indirect ways in the central nervous system (CNS). Fractalkine/CX3CR1 axis regulates microglial activation and function, neuronal survival and synaptic function by controlling the release of inflammatory cytokines and synaptic plasticity in the course of the neurological disease. The multiple functions of fractalkine/CX3CR1 make it exert neuroprotective or neurotoxic effects, which determines the pathogenesis. However, the role of fractalkine/CX3CR1 in the CNS remains controversial. Whether it can be used as a therapeutic target for neurological diseases needs to be further investigated. In this review, we summarize the studies highlighting fractalkine/CX3CR1-mediated effects and discuss the potential neurotoxic and neuroprotective actions of fractalkine/CX3CR1 in brain injury for providing useful insights into the potential applications of fractalkine/CX3CR1 in neurological diseases.