关键词： telemedicine   technology   telegenetics   telepathology   telerehabilitation  

摘要： Introduction: Telemedicine represents an emerging model for the assessment and management of various neurological disorders. Methods: We sought to discuss opportunities and challenges for the integration of telemedicine in the management of common and uncommon neurological disorders by reviewing and appraising studies that evaluate telemedicine as a means to facilitate the access to care, deliver highly specialized visits, diagnostic consultations, rehabilitation, and remote monitoring of neurological disorders. Results: Opportunities for telemedicine in neurological disorders include the replacement of or complement to in-office evaluations, decreased time between follow-up visits, reduction in disparities in access to healthcare, and promotion of education and training through interactions between primary care physicians and tertiary referral centers. Critical challenges include the integration of the systems for data monitoring with an easy-to-use, secure, and cost-effective platform that is both widely adopted by patients and healthcare systems and embraced by international scientific societies. Conclusions: Multiple applications may spawn from a model based on digitalized healthcare services. Integrated efforts from multiple stakeholders will be required to develop an interoperable software platform capable of providing not only a holistic approach to care but also one that reduces disparities in the access to care.

关键词： Epidemiology   Health policy   Health services   Stroke  

摘要： The Global Burden of Disease, Injuries and Risk Factors 2016 study has shown that neurological diseases have the highest burden and that this burden is increasing. Stroke is the biggest contributor, highlighting a need to improve resources globally for stroke prevention, management and rehabilitation.

关键词： 《中文核心期刊要目总览》   文献计量学   神经疾病   研究人员   专家评审   精神病学   神经病学   北京大学  

摘要： 《中国现代神经疾病杂志》主编:我们谨此郑重通知:依据文献计量学的原理和方法,经研究人员对相关文献的检索、统计和分析,以及学科专家评审,贵刊《中国现代神经疾病杂志》入编《中文核心期刊要目总览》2017年版(即第8版)之"神经病学与精神病学"类的核心期刊。该书由北京大学出版社出版。

关键词： 神经病学与精神病学期刊   网站   微信公众平台   数字出版  

摘要： 分析我国神经病学与精神病学中文核心期刊网站建设和微信公众平台自定义菜单的设置情况,结果发现期刊网站发布的信息主要包括期刊信息、编委会、投稿指南、期刊订阅等静态信息和期刊论文、期刊动态、行业动态等动态信息,且动态信息存在不同程度的更新时滞。特色栏目较少,缺乏对内容的深度加工,在专题、热点文章的分类传播,E-mail/RSS推送、医学继续教育、发布在线视频讲座、为专家、读者、作者提供在线访谈方面比较薄弱。期刊微信公众平台自定义菜单的功能多围绕期刊、论文、投稿等方面,主要与期刊网站、采编系统链接,少数期刊实现了与微电台、微店、社区与论坛、读者俱乐部等的链接。建议期刊重视对期刊内容资源的增值开发和利用,充分挖掘微信公众平台自定义菜单的功能和价值,实现我国神经病学与精神病学期刊信息服务能力的不断提升。

关键词： 《中文核心期刊要目总览》   《中华老年心脑血管病杂志》   文献计量学   研究人员   专家评审   精神病学   神经病学   北京大学  

摘要： 《中华老年心脑血管病杂志》主编:我们谨此郑重通知:依据文献计量学的原理和方法,经研究人员对相关文献的检索、统计和分析,以及学科专家评审,贵刊《中华老年心脑血管病杂志》入编《中文核心期刊要目总览》2017年版(即第8版)之"神经病学与精神病学"类的核心期刊。该书由北京大学出版社出版。

关键词： 大脑   衰老   适度运动   思维能力   神经病学   临床试验   研究人员   执行功能  

摘要： 在线发表在《神经病学杂志》(Journal of Neurology)(2018-12-19)杂志上一项近期临床试验发现,步行和其他类型的适度运动可能有助于为那些正在失去精神敏锐度的老年人。该研究的重点是老年人,他们在记忆和思维能力方面存在较轻微的问题。研究人员发现,经过6个月的适度运动如步行或踩踏一辆固定的自行车,结果表明,锻炼者的执行功能得到了改善,包括大脑注意力、调节行为、组织起来并实现目标的能力。而那些同时也改为健康饮食的人,包括多吃水果和蔬菜,则显示出更大的收益。

关键词： 卒中   防治   中国   四川大学华西医院   解读   神经病学   脑血管病   疾病负担  

摘要： 2018年,《柳叶刀-神经病学》杂志邀请中国各地脑血管病领域的领军专家组成作者团队,由四川大学华西医院刘鸣教授牵头作为唯一通讯作者,华西医院吴思缈医生和吴波教授为共同第一作者,对2007—2018年间中国卒中疾病负担和防治相关的研究数据进行了时间和空间多重对比和全面分析,揭示了我国卒中发生、发展及预后的疾病规律,指出了卒中防治的现状、取得的进步和面临的挑战,并提出了未来的应对策略。《中国卒中防治:进展与挑战》于2019年3月在《柳叶刀-神经病学》线上发表,4月正式见刊。

关键词： Coronary artery disease   Mental stress   Childhood trauma   Insula   Hippocampus   Cardiovascular  

摘要： Background: Early childhood trauma is known to independently increase adverse outcome risk in coronary artery disease (CAD) patients, although the neurological correlates are not well understood. The purpose of this study was to examine whether early childhood trauma alters neural responses to acute mental stress in CAD patients. Methods: Participants (n = 152) with CAD underwent brain imaging with High Resolution Positron Emission Tomography and radiolabeled water during control (verbal counting, neutral speaking) and mental stress (mental arithmetic, public speaking). Traumatic events in childhood were assessed with the Early Trauma Inventory (ETI-SR-SF) and participants were separated by presence (ETI +) or absence (ETI-) of early childhood trauma. Brain activity during mental stress was compared between ETI + and ETI-. Results: Compared to ETI-, ETI + experienced greater (p < 0.005) activations during mental stress within the left anterior cingulate, bilateral frontal lobe and deactivations (p < 0.005) within the left insula, left para-hippocampal gyrus, right dorsal anterior cingulate, bilateral cerebellum, bilateral fusiform gyrus, left inferior temporal gyrus, and right parietal lobe. Significant (p < 0.005) positive correlations between brain activation and ETI-SR-SF scores were observed within the left hippocampus, bilateral frontal lobe, left occipital cuneus, and bilateral temporal lobe. Limitations: Results in non-CAD samples may differ and ETI may be subject to recall bias. Conclusion: Early childhood trauma exacerbated activations in stress-responsive limbic and cognitive brain areas with direct and indirect connections to the heart, potentially contributing to adverse outcomes in CAD patients.

关键词： anticoagulants   atrial fibrillation   left atrial appendage occlusion   stroke  

摘要： Objectives This study sought to investigate neurological disability after ischemic cerebrovascular events in patients treated with left atrial appendage (LAA) occlusion compared with those on warfarin. Background Prior studies demonstrated that cerebrovascular events after LAA occlusion in patients with nonvalvular atrial fibrillation (NVAF) is largely nondisabling. Methods From the 1,189 patients in the Korean LAA Occlusion and European Amplatzer Cardiac Plug Multi-Center Registry, 24 patients who experienced ischemic cerebrovascular events after LAA occlusion were enrolled. The neurological outcomes were compared with those in 68 patients who experienced an ischemic cerebrovascular event while on warfarin (Yonsei Stroke Registry). A modified Rankin scale (mRS) score of 3-6 categorized the cerebrovascular event as disabling. The mRS at discharge and at 3 and 12 months postcerebrovascular event in the two groups was compared. Results The percentages of disabling cerebrovascular events were 37.5% and 58.8% at discharge (P = 0.07), 20.8% and 42.6% at 3 months (P = 0.08), and 12.5% and 39.7% at 12 months (P = 0.02) in the LAA occlusion and warfarin groups, respectively. The mRS was significantly lower in the LAA occlusion group at discharge and at 3 months (P < 0.01) and 12 months (P < 0.01) postcerebrovascular event despite no significant difference in mRS before cerebrovascular events (P = 0.98). Patients in the LAA occlusion group demonstrated a significant reduction in mRS between discharge and 12 months (P < 0.01), unlike patients in the warfarin group (P = 0.10). Conclusions Ischemic cerebrovascular events in patients who previously underwent percutaneous LAA occlusion for NVAF were more favorable than in patients on warfarin.