关键词： 神经病学   重症医学   神经重症医学   基于问题式教学法(PBL)  

摘要： 目的为解决重症医学专业学生在神经病学教学过程中教学方法单一问题,将基于问题式教学法(PBL)应用于重症医学专业神经病学教学实践中并探索其效果。方法纳入贵州医科大学2014级重症医学专业学生52名,按配对法结合自愿原则分为PBL教学方法组(PBL组)以及传统教学方法组(对照组)。利用临床教学质量评价量表和期末考试成绩评价PBL教学法的教学效果。结果同对照组比较,PBL组学生的期末考试成绩及学生对教学质量评价的评分均较高,差异均具有统计学意义(P<0.05);同行评议对比分析显示,PBL组的评分也较对照组高(P<0.05)。结论PBL教学法能够改善重症医学专业神经病学的教学效果。

关键词： 神经病学   多发性硬化   癫痫   帕金森病   头痛  

摘要： 第十三届世界神经病学争议大会(the 13th World Congress on Controversies in Neurology,CONy 2019)(***)于2019年4月4日至7日在西班牙马德里成功召开。该会议通过学术报告和辩论会的形式,讨论神经病学方面最新及最具挑战的趋势和议题,涉及神经眼科、睡眠障碍、疼痛管理.

关键词： 翻转课堂   微信平台   神经系统查体   神经病学   教学方法   临床教学  

摘要： 目的探索基于微信平台下的翻转课堂对神经系统查体教学的应用和效果评价。方法选取2017 年7 月—2018 年5 月在徐州医科大学第二附属医院实习的临床医学专业学生85 人为教学对象,随机分为实验组42 人,对照组43 人。由同一名教师进行神经系统查体教学。其中实验组采用基于微信平台的翻转课堂教学法,对照组采用传统教学法。比较两组学生的理论和技能操作成绩,并通过问卷的形式评价主观教学效果。结果实验组和对照组相比,实验组理论[(92.79±2.53)vs (88.07±3.51)]和技能操作[(94.64±2.24)vs (88.62±3.87)]成绩更好(P <0.05),80%以上的实验组学生认为新的教学法在课堂活跃程度、自主学习能力、学习节奏控制、知识拓展程度、知识牢固程度、师生互动程度等方面均优于传统教学法。结论基于微信平台的翻转课堂能够提高学生的成绩,且学生满意度更高。

关键词： 临床神经病学   公众   杂志   信息反馈   搜索  

摘要： 为了加强与广大读者、作者以及专家的沟通,及时进行信息反馈,《临床神经病学杂志》微信公众平台于2015年8月正式开通,欢迎大家关注!您可通过以下三种方式关注《临床神经病学杂志》微信公众平台:1、搜索公众订阅号名称"临床神经病学杂志"添加关注;2、搜索微信号"lcsjbx"添加关注;3、扫描位于本刊目次页右上角的微信二维码。

关键词： 临床神经病学   稿酬   杂志   财务部门   作者   邮局   论文   再次  

摘要： 本刊刊用的论文在当期杂志发行后3周内将会给第一作者寄出稿酬。本刊往期中已多次刊登"关于及时领取稿酬的通知",对汇款逾期未领被邮局退回汇款不再重寄。目前仍有作者未及时领取汇款,被邮局退回。本刊现再次通知,请作者在论文刊登后注意查收和及时领取稿酬,如稿酬未及时领取被邮局退回,则交上级主管财务部门,本刊不再重寄。特再次告之。

关键词： 中国医师协会   神经疾病   杂志   临床科研工作   临床病理报告   订阅   流行病学调查   神经病学  

摘要： 《中国现代神经疾病杂志》为国家卫生健康委员会主管、中国医师协会主办的神经病学类专业期刊。办刊宗旨为:理论与实践相结合、普及与提高相结合,充分反映我国神经内外科临床科研工作重大进展,促进国内外学术交流。所设栏目包括述评、专论、论著、临床病理报告、应用神经解剖学、神经影像学、循证神经病学、流行病学调查研究、基础研究、临床研究、综述、临床医学图像、病例报告、临床病理(例)讨论、新技术新方法等。

关键词： 《中文核心期刊要目总览》   《中华老年心脑血管病杂志》   文献计量学   研究人员   专家评审   精神病学   神经病学   北京大学  

摘要： 《中华老年心脑血管病杂志》主编:我们谨此郑重通知:依据文献计量学的原理和方法,经研究人员对相关文献的检索、统计和分析,以及学科专家评审,贵刊《中华老年心脑血管病杂志》入编《中文核心期刊要目总览》2017年版(即第8版)之“神经病学与精神病学”类的核心期刊。该书由北京大学出版社出版。

关键词： axial diffusivity   diffusion tensor imaging   fractional anisotropy   longitudinal analysis   ordinal regression analysis   outcome measures   radial diffusivity   traumatic brain injury  

摘要： Traumatic axonal injury (TAI) is the main cause of cognitive and psychological disfunction after a traumatic brain injury (TBI). Diffusion tensor imaging (DTI) is considered a useful technique for indirect assessment of white matter (WM) integrity after a TBI. Scattered WM alterations and its relationship with patient severity have been discovered in normal appearing conventional magnetic resonance imaging (MRI) studies based on DTI sequences. However, there is a lack of large sample studies on the longitudinal changes of DTI metrics to be used to determine the temporal profile after head injury and its association with patient outcome. We performed a prospective observational study in 118 moderate-to-severe TBI patients. The study included clinical outcome assessment based on the Glasgow Outcome Scale Extended (GOSE) and serial DTI studies in the early subacute setting (< 60 days) and 6 and 12 months after injury. Fractional anisotropy (FA) and axial and radial diffusivities (AD and RD, respectively) were measured in the three portions of corpus callosum (genu, body, splenium) at each time-point and compared with normalized values from an age-matched control group. Longitudinal FA analysis and its correlation with patient improvement also was done by non-parametric testing and ordinal regression analysis. Our main results indicated that between all the time-points, dynamic changes in DTI metrics in all three portions of corpus callosum were detected, but TBI patients continued to show significantly lower FA and AD values and higher RD values compared with controls. We also have discovered differences in the change of DTI metrics among different time-points in patient subgroups according with their outcome improvement. In conclusion, even without normalization of DTI metrics in the long-term, knowledge of the temporal profile of change in DTI metrics can provide important information about patients' clinical recovery after TBI.

关键词： Inflammation   Neurological markers   Health-related quality of life   Well-being   Older adults  

摘要： Objectives: Stressful experiences, poor self-rated health, and negative emotional states have been implicated with higher levels of inflammatory markers and lower levels of neurotrophic factors in some healthy adults and clinical populations, but these relationships are unclear in the elderly. This study aimed to identify the associations between systemic inflammatory and neurological markers with well-being and health-related quality of life (HR-QoL) in independently living elderly people. Design: Cross-sectional study. Setting and participants: A total of 268 men and women aged >= 65 years living independently in retirement communities in Melbourne, Australia. Measures: Questionnaires were used to assess HR-QoL [Short Form (SF)-36 version 2] and well-being (Personal Wellbeing Index). Serum inflammatory cytokines [interleukin (IL)-4, IL-6, IL-1 beta, IL-8, IL-10, tumor necrosis factor (TNF)-alpha, and high sensitive C-reactive protein (hs-CRP)] were standardised to Z-scores and used to calculate pro- and anti-inflammatory composite score and an overall composite inflammatory index. Plasma levels of the neurological markers amyloid beta (1-40) and amyloid beta (1-42), brain derived neurotrophic factor (BDNF), insulin-like growth factor-1 (IGF-1) and vascular endothelial growth factor (VEGF), were also assessed. Results: No significant associations were found between any inflammatory or neurological marker with HR-OoL or well-being, with the exception that lower perceptions of the HR-QoL vitality subscale were associated with higher levels of hs-CRP [unstandardized beta-coefficient (beta): - 1.50;95% CI: - 2.53, - 0.46;P = 0.004] and Zscores in the pro-inflammatory composite score (beta = - 2.06;95% CI: - 3.49, - 0.62;P = 0.005). Conclusions/implications: In elderly people residing in independent living retirement communities, there was no consistent evidence indicating that circulating inflammatory or neurological markers were associated with the key physical or men