关键词： 北京大学出版社   文献计量学   《中文核心期刊要目总览》   核心期刊   神经病学   精神病学   专家评审   中华神经医学杂志  

摘要： 《中华神经医学杂志》主编:我们谨此郑重通知:依据文献计量学的原理和方法,经研究人员对相关文献的检索、统计和分析,以及学科专家评审,贵刊《中华神经医学杂志》入编《中文核心期刊要目总览》2017年版(即第8版)之“神经病学与精神病学”类的核心期刊。该书由北京大学出版社出版。

关键词： 来源期刊   神经免疫学   科研成果   科研人员   中国学术期刊   中国免疫学会   神经病学   学术性期刊  

摘要： 《中国神经免疫学和神经病学杂志》是全国惟一与神经免疫学相关的神经病学学术性期刊,由卫健委主管,北京医院、中国免疫学会神经免疫分会主办,国内外公开发行。本刊以从事神经免疫学和神经病学临床和科研人员等为主要读者对象,报道神经疾病领域尤其是神经免疫学领域的科研成果。本刊属中国科技论文统计源期刊、中国科技核心期刊、中国科技引文数据库来源期刊与中国学术期刊综合评价数据库来源期刊等。

关键词： 病例讨论   医学专业   神经病学   学术交流平台   编辑部编辑   有奖征文启事   癫痫   学术期刊  

摘要： 癫痫是神经病学临床工作的热点、难点之一,作为癫痫学科学术交流平台的《癫痫杂志》于2015年7月创刊。《癫痫杂志》是由教育部主管,四川大学主办,《癫痫杂志》编辑部编辑出版的医学专业类学术期刊,系中国抗癫痫协会会刊。本刊分为论著、综述、Epilepsia专栏、病例讨论、世界舞台·中国好声音、纪要等栏目。为了更好地促进我国癫痫专业领域的科研进展,提高我国癫痫诊疗的规范化程度和学术水平,现特举办有奖征文活动。

关键词： 中文核心期刊要目总览   来源期刊   神经免疫学   科研成果   科研人员   中国学术期刊   中国免疫学会   神经病学  

摘要： 《中国神经免疫学和神经病学杂志》是全国唯一与神经免疫学相关的神经病学学术性期刊,由国家卫健委主管,北京医院、中国免疫学会神经免疫分会主办,国内外公开发行。本刊以从事神经免疫学和神经病学临床和科研人员等为主要读者对象,报道神经疾病领域尤其是神经免疫学领域的科研成果。本刊属《中文核心期刊要目总览(2017版)》收录期刊、中国科技论文统计源期刊、中国科技核心期刊、中国科技引文数据库来源期刊与中国学术期刊综合评价数据库来源期刊等。

关键词： 神经精神疾病   康复医学   精神病学   神经遗传学   神经病学   科研方法   科研成果   核心期刊  

摘要： 《中国神经精神疾病杂志》为我国神经病学与精神病学核心期刊,国内外公开发行。本刊以广大神经内科、神经外科、精神科及相关学科(包括神经生物学、神经遗传学及康复医学等)医师为主要读者,报道神经精神学科领域领先的科研方法、科研成果和临床诊疗经验,以及对神经精神疾病临床有指导意义的基础理论研究。一直被《中文核心期刊要目总览》、《中国科技论文统计源期刊》、中国科学引文数据库(CSCD)等收录为核心期刊。

关键词： gray matter volume   mCCA plus jICA   motor abnormalities   neurological soft signs   resting-state functional MRI   schizophrenia spectrum disorders  

摘要： Neurological soft signs (NSS) comprise a broad range of subtle neurological deficits and are considered to represent external markers of sensorimotor dysfunction frequently found in mental disorders of presumed neurodevelopmental origin. Although NSS frequently occur in schizophrenia spectrum disorders (SSD), specific patterns of co-altered brain structure and function underlying NSS in SSD have not been investigated so far. It is unclear whether gray matter volume (GMV) alterations or aberrant brain activity or a combination of both, are associated with NSS in SSD. Here, 37 right-handed SSD patients and 37 matched healthy controls underwent motor assessment and magnetic resonance imaging (MRI) at 3 T. NSS were examined on the Heidelberg NSS scale. We used a multivariate data fusion technique for multimodal MRI data-multiset canonical correlation and joint independent component analysis (mCCA + jICA)-to investigate co-altered patterns of GMV and intrinsic neural fluctuations (INF) in SSD patients exhibiting NSS. The mCCA + jICA model indicated two joint group-discriminating components (temporoparietal/cortical sensorimotor and frontocerebellar/frontoparietal networks) and one modality-specific group-discriminating component (p < .05, FDR corrected). NSS motor score was associated with joint frontocerebellar/frontoparietal networks in SSD patients. This study highlights complex neural pathomechanisms underlying NSS in SSD suggesting aberrant structure and function, predominantly in cortical and cerebellar systems that critically subserve sensorimotor dynamics and psychomotor organization.

关键词： Cardiogenic shock   Neurological outcome   Short-term mechanical circulatory support   ECMO   Survival   Mechanical circulatory support   Impella  

摘要： OBJECTIVES: Peripheral venoarterial extracorporeal life support (ECLS) for the treatment of cardiogenic shock has shown to improve survival but is associated with complications. However, if the patient cannot be weaned from ECLS, their therapy options are limited. Although durable left ventricular assist device implantation might be an option in such cases, an unclear neurological outcome is often a contraindication. We hypothesize that Impella 5.0 therapy provides sufficient circulatory support while avoiding ECLS-related complications, thereby allowing for an adequate evaluation of a patient's neurological state and facilitating further treatment options. METHODS: We retrospectively reviewed data from 22 ECLS patients (mean age 56.5 +/- 10.7 years) with an unclear neurological status who underwent Impella 5.0 implantation between January 2016 and July 2018 in our institution. Neurological status was evaluated on a daily basis using the cerebral performance category score and the modified Rankin scale. RESULTS: Sixteen patients (72.7%) were resuscitated before ECLS implantation and 13 patients (59.1%) had acute myocardial infarction. The mean duration on ECLS before Impella 5.0 implantation was 9.3 +/- 1.7 days. All patients were successfully weaned from ECLS by Impella 5.0 implantation via the axillary artery. The mean duration on Impella 5.0 was 16.3 +/- 4.7 days. In surviving patients, both quantitative measurements of cerebral performance improved after 30 days compared to the baseline (P < 0.01). Six patients (27.3%) were bridged to a durable left ventricular assist device. In 9 patients (40.9%), myocardial function recovered during Impella 5.0 support and the device was successfully explanted. The 30-day survival rate was 68.2%. CONCLUSIONS: Impella 5.0 support provides a bridge-to-decision option for patients following ECLS implantation and leads to left ventricular unloading. It allows further evaluation of a patient's neurological situation and facilitates

摘要： Cholinergic dysfunction is involved in a range of neurological and psychiatric disorders, including schizophrenia, dementia and Lewy body disease (LBD), leading to widespread use of cholinergic therapies. However, such drugs have focused on increasing the availability of acetylcholine (ACh) generally, with relatively little work done on the muscarinic system and specific muscarinic receptor subtypes. In this review, we provide an overview of the major cholinergic pathways and cholinergic muscarinic receptors in the human brain and evidence for their dysfunction in several neurological and psychiatric disorders. We discuss how the selectivity of cholinergic system dysfunction suggests that targeted cholinergic therapeutics to the muscarinic receptor subtypes will be vital in treating several disorders associated with cognitive dysfunction and behavioural and psychological symptoms.