关键词： 科研诚信   ID码   临床神经病学   交流研究成果   标识码   增值服务   投稿须知   OSI  

摘要： 《临床神经病学杂志》从2019年8月起正式加入OSID(Open Science Identity)开放科学计划。将通过在文章上添加开放科学二维标识码(OSID码),为读者和作者提供一个与业界同行和专家进行学术交流研究成果的途径,同时提供系列增值服务,提升论文的科研诚信。投稿本刊的作者请查看本刊投稿须知,注册“OSID作者助手”工具账号,使用工具创建OSID码,按照要求将稿件中加入OSID码一起投到本刊。

摘要： 《国际神经病学神经外科学杂志》创刊于1974年,由教育部主管,中南大学和中南大学湘雅医院主办。是目前国内唯一一本同时涵盖神经病学和神经外科学两个相联学科的专业学术期刊。本刊被收录为“中国科技核心期刊(中国科技论文统计源期刊)”。

关键词： 脑梗死   脑桥   神经病学表现   危险因素  

摘要： 目的探讨轻度脑桥梗死后早期神经功能缺损的影响因素。方法选择121例轻型脑桥梗死患者为研究对象,根据美国国立卫生研究院卒中量表(NIHSS)评分分为神经功能恶化组(41例)和神经功能非恶化组(80例),回顾性收集、比较两组患者一般资料、实验室检查及影像学相关资料结果,并进行logistic回归分析。结果两组患者间糖尿病史、空腹血糖、出院时NIHSS评分、梗死部位、梗死灶分布、梗死层面最大直径、基底动脉狭窄、脑室旁脑白质高信号(WMH)及皮质下WMH差异有统计学意义(P<0.05)。logistic回归分析显示,脑桥下部梗死、累及脑桥腹侧表面梗死、基底动脉狭窄≥50%、脑室旁重度WMH、皮质下重度WMH为神经功能恶化的独立影响因素(P<0.05)。结论脑桥下部梗死、累底脑桥腹侧表面梗死、基底动脉狭窄≥50%、脑室旁重度WMH、皮质下重度WMH为轻度脑桥梗死患者神经功能恶化的独立影响因素。

摘要： Compare and analyze the indicators of clinical neurological examination, MRI, auricular, su-jok diagnosis in patients after a stroke and with chronic cerebrovascular disorder to further substantiate the use of complementary methods in clinical practice, primarily as an express method. Group І-56 patients after a stroke in the early residual period, age 64 ± 7.1, including 23 men and 31 women. 48 (85.7%) patients had a stroke in the carotid vascular basin, 8 (14.3%) - in vertebral-basilar. Group II-30 patients with signs of chronic cerebrovascular disorders. All patients underwent clinical-neurological examination, MRI-examination, assessment of the condition of the auricula (skin and subcutaneous tissues) and the assessment of the distal phalanges of the thumbs and the hallux - their circumference at the level of the middle of the nail plate in mm was measured. All indicators were compared among each patient and I–II group indicators were compared with the data of 30 patients without vascular pathology of the brain. Clinical and neurological examination, which included the collection of complaints, anamnesis, the evaluation of objective indicators and MRI brain examination, verified the presence of a stroke and / or presence of chronic cerebrovascular disorders. All patients (100%) of first and second groups, regardless of gender and age, had trophic changes of varying degrees of severity in the area of the earlobe, ear antitragus, scaphoid fossa, posterior ear furrow, hypotrophy on both sides, more pronounced homolateral foci of a stroke, the presence of Frank’s furrow, mesh in the form of shallow furrows, excoriations in the area of the anti-tragus. Compliance of the changes was observed depending on the localization of the stroke: shallow furrows with vertebro-basilar strokes in the upper part of the ear lobe, the carotid stroke — in the mid-lower part. In 62%, there was a sharp change in the color of the skin of the auricle at the level of the posterior auricle

关键词： 杂志发行   财务部门   稿酬   临床神经病学   汇款   通知   查收   邮局  

摘要： 本刊刊用的论文在当期杂志发行后3周内将会给第一作者寄出稿酬。本刊往期中已多次刊登“关于及时领取稿酬的通知”,对汇款逾期未领被邮局退回汇款不再重寄。目前仍有作者未及时领取汇款,被邮局退回。本刊现再次通知,请作者在论文刊登后注意查收和及时领取稿酬,如稿酬未及时领取被邮局退回,则交上级主管财务部门,本刊不再重寄。特再次告之。

关键词： 神经免疫学   华山医院   自身免疫病   神经内科   神经病学   治疗新进展   交叉学科   靶向药物  

摘要： 由复旦大学附属华山医院神经内科、复旦大学神经病学研究所和复旦大学附属华山医院教育处举办的国家级继续教育项目“第六届华山医院临床神经免疫学新进展”学习班拟定于2020年8月20~23日在复旦大学附属华山医院召开。学习班主旨为“肿瘤、靶向药物与神经免疫”,聚焦神经系统自身免疫病诊断与治疗新进展,尤其关注近年来肿瘤靶向药物、免疫药物应用于自身免疫病领域,以及恶性肿瘤(尤其是血液系统肿瘤)与神经免疫学交叉学科研究新进展。

关键词： 临床神经病学   微信公众平台   信息反馈   微信号   三种方式   杂志  

摘要： 为了加强与广大读者、作者以及专家的沟通,及时进行信息反馈,《临床神经病学杂志》微信公众平台于2015年8月正式开通,欢迎大家关注!您可通过以下三种方式关注《临床神经病学杂志》微信公众平台:1、搜索公众订阅号名称“临床神经病学杂志”添加关注;2、搜索微信号“lcsjbx”添加关注;3、扫描位于本刊目次页右上角的微信二维码。

关键词： Blood-brain barrier   Stem cells   Diseases modeling   Endothelial cells   Neurological diseases   Induced pluripotent stem cells  

摘要： The blood-brain barrier (BBB) is a component of the neurovascular unit formed by specialized brain microvascular endothelial cells (BMECs) surrounded by a specific basement membrane interacting with astrocytes, neurons, and pericytes. The BBB plays an essential function in the maintenance of brain homeostasis, by providing a physical and chemical barrier against pathogens and xenobiotics. Although the disruption of the BBB occurs with several neurological disorders, the scarcity of patient material source and lack of reliability of current in vitro models hindered our ability to model the BBB during such neurological conditions. The development of novel in vitro models based on patient-derived stem cells opened new venues in modeling the human BBB in vitro, by being more accurate than existing in vitro models, but also bringing such models closer to the in vivo setting. In addition, patient-derived models of the BBB opens the avenue to address the contribution of genetic factors commonly associated with certain neurological diseases on the BBB pathophysiology. This review provides a comprehensive understanding of the BBB, the current development of stem cell-based models in the field, the current challenges and limitations of such models.

关键词： 办刊宗旨   中国医师协会   神经疾病   神经解剖学   普及与提高   神经病学   专业期刊   神经内外科  

摘要： 《中国现代神经疾病杂志》为国家卫生健康委员会主管、中国医师协会主办的神经病学类专业期刊。办刊宗旨为:理论与实践相结合、普及与提高相结合,充分反映我国神经内外科临床科研工作重大进展,促进国内外学术交流。所设栏目包括述评、专论、论著、临床病理报告、应用神经解剖学、神经影像学、循证神经病学、流行病学调查研究、基础研究、临床研究、综述、临床医学图像、病例报告、临床病理(例)讨论、新技术新方法等。